Department of Urology, Skåne University Hospital, University of Lund, S-20502 Malmö, Sweden.
Int J Antimicrob Agents. 2011 Dec;38 Suppl:58-63. doi: 10.1016/j.ijantimicag.2011.09.008. Epub 2011 Oct 12.
Surgical site infections (SSI) including urinary tract infections (UTI) cause a significant morbidity in urological surgery. Antibiotic prophylaxis is one of several factors impacting on infection rates. Antibiotic prophylaxis is relevant only for clean and clean-contaminated operations and in the absence of bacterial growth in the urine. Strict classification of urological procedures is lacking, but a proposal is presented elsewhere. Only TURP and transrectal core prostate biopsy are well documented. The present review confirms that there is a lack of hard data, insufficient consistency in classification and definitions, and that new well-powered RCT and large multicentre quality cohort studies including risk factor analysis are necessary to improve recommendations for antibiotic prophylaxis in urologic surgery.
手术部位感染（SSI）包括尿路感染（UTI），会给泌尿外科手术带来显著的发病率。抗生素预防是影响感染率的几个因素之一。抗生素预防仅适用于清洁和清洁污染手术，并且尿液中没有细菌生长。泌尿外科手术的严格分类缺乏，但在其他地方提出了一项建议。只有 TURP 和经直肠核心前列腺活检有充分的记录。本综述证实，缺乏硬性数据，分类和定义不够一致，需要进行新的、有力的 RCT 和大型多中心质量队列研究，包括风险因素分析，以改善泌尿外科手术中抗生素预防的建议。
