Wirth F H, Numerof B, Pleban P, Neylan M J
Department of Pediatrics, Eastern Virginia Medical School, Norfolk.
J Pediatr. 1990 Aug;117(2 Pt 1):283-7. doi: 10.1016/s0022-3476(05)80548-7.
To determine whether a reduction of dietary lactose affects mineral absorption in preterm infants, a controlled, randomized, 72-hour balance study was conducted with very low birth weight infants (birth weights less than 1400 gm) fed Similac Special Care formula with a 50:50 carbohydrate blend of glucose polymers and lactose (n = 8) or a nearly identical formula with 100% carbohydrate as lactose (n = 10). The studies were conducted after at least 3 consecutive days of full oral feeds at a mean age of approximately 23 days. There was no difference between groups in percentage of apparent absorption of calcium, phosphorus, magnesium, zinc, copper, or manganese. Retention of these nutrients was similar to or greater than that which occurs in utero. Calcium absorption was 75% of intake. These results indicate that reducing the lactose content of premature-infant formulas to 50% of the carbohydrate does not impair mineral absorption.
为了确定减少膳食乳糖是否会影响早产儿的矿物质吸收，对出生体重极低（出生体重低于1400克）的婴儿进行了一项为期72小时的对照、随机平衡研究，这些婴儿喂食含有葡萄糖聚合物和乳糖的50:50碳水化合物混合物的Similac特殊护理配方奶粉（n = 8）或几乎相同的以100%乳糖作为碳水化合物的配方奶粉（n = 10）。研究在平均年龄约23天、至少连续3天完全经口喂养后进行。两组之间钙、磷、镁、锌、铜或锰的表观吸收率没有差异。这些营养素的潴留与子宫内的情况相似或更高。钙吸收量为摄入量的75%。这些结果表明，将早产儿配方奶粉中的乳糖含量降低至碳水化合物的50%不会损害矿物质吸收。
