Medical University of Graz, Department of Internal Medicine, Auenbruggerplatz 15, 8036 Graz, Austria.
Blood Rev. 2012 Jan;26(1):33-42. doi: 10.1016/j.blre.2011.09.003. Epub 2011 Oct 11.
Although blood donation is generally safe, a variety of risks and complications exist, the most common being iron deficiency, vasovagal reactions and citrate-related events. In the last decades, extensive efforts have significantly improved recipient and product safety, but there is still great potential to optimise donor care. Many therapies in modern medicine depend on the prompt availability of blood products, therefore it is crucial to maintain a motivated and healthy donor pool in view of a limited number of healthy volunteers willing and able to give blood or blood components. We present a comprehensive review on adverse events addressing all types of blood donation including whole blood, plasma, platelet, peripheral blood stem cell, leucocyte and bone marrow donation. In addition, we outline strategies for the prevention and treatment of these events and give a blueprint for future research in this field.
虽然献血通常是安全的，但存在多种风险和并发症，最常见的是缺铁、血管迷走神经性反应和柠檬酸盐相关事件。在过去的几十年中，大量的努力显著提高了受血者和产品的安全性，但仍有很大的潜力来优化献血者的护理。现代医学中的许多疗法都依赖于血液制品的即时供应，因此，鉴于愿意并能够献血或血液成分的健康志愿者人数有限，保持一个有积极性和健康的献血者群体至关重要。我们全面回顾了所有类型的献血（包括全血、血浆、血小板、外周血干细胞、白细胞和骨髓捐献）中涉及的不良事件。此外，我们还概述了预防和治疗这些事件的策略，并为该领域的未来研究制定了蓝图。
