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实体器官移植中供者源性传染病传播的统一定义。

Uniform definitions for donor-derived infectious disease transmissions in solid organ transplantation.

出版信息

Transplantation. 2011 Dec 27;92(12):1297-300. doi: 10.1097/TP.0b013e318236cd02.

DOI:10.1097/TP.0b013e318236cd02
PMID:21996654
Abstract

High-profile cases of infectious diseases transmitted from organ donors to transplant recipients, such as the transmission of human immunodeficiency virus, have driven policy globally. Many nations have or are developing regulations requiring reporting and investigation of such disease transmissions as part of broader biovigilance programs for all substances of human origin. A group of experts (see Acknowledgments) developed definitions for proven, probable, possible, unlikely, excluded, intervened upon without documented transmission, and positive assay without apparent disease transmission events that should be used, as a starting point, to standardize nomenclature and facilitate global tracking and study of such infectious disease transmissions.

摘要

高知名度的传染病病例,如艾滋病毒,从器官捐献者传播给移植受者,推动了全球的政策制定。许多国家已经或正在制定法规,要求报告和调查此类疾病的传播,作为更广泛的人体来源物质生物监测计划的一部分。一组专家(见鸣谢)制定了已证实、可能、可能、不太可能、排除、未经记录传播的干预、以及无明显疾病传播事件的阳性检测的定义,这些定义应作为起点,用于标准化命名法并促进此类传染病传播的全球跟踪和研究。

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