Curatolo Andrea, Kennedy Brendan F, Sampson David D
Optical+Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia.
Opt Express. 2011 Sep 26;19(20):19480-5. doi: 10.1364/OE.19.019480.
We present a three-dimensional structured tissue-mimicking phantom for use in optical coherence tomography (OCT). The phantom was fabricated from a silicone matrix and titanium dioxide additive using a lithographic casting method capable of producing a wide range of well-defined geometries with optical contrast and mesoscopic feature sizes relevant to OCT. We describe the fabrication, characterization and OCT imaging of two phantoms and demonstrate their utility in assessing the performance of a spatial-diversity speckle reduction technique. Such phantoms will be important in the development of standards in OCT, as well as in enabling quantitative performance assessment.
我们展示了一种用于光学相干断层扫描（OCT）的三维结构化组织模拟体模。该体模由硅酮基质和二氧化钛添加剂制成，采用光刻铸造法，能够制造出具有光学对比度且与OCT相关的介观特征尺寸的各种明确几何形状。我们描述了两个体模的制造、表征和OCT成像，并展示了它们在评估空间分集散斑减少技术性能方面的效用。这种体模对于OCT标准的制定以及进行定量性能评估都将具有重要意义。
