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[1例晚期结肠癌所致骨髓播散性癌病伴弥散性血管内凝血经mFOLFOX6治疗的病例]

[A case of disseminated carcinomatosis of bone marrow with disseminated intravascular coagulation caused by advanced colon cancer treated by mFOLFOX6].

作者信息

Isozaki Yutaka, Yamanishi Masayoshi, Utsunomiya Sakae, Yamaguchi Shunsuke, Okita Mika, Matsumoto Naoyuki, Nagao Yasuyuki, Oyamada Hirokazu, Kokura Satoshi, Naito Yuji, Yoshikawa Toshikazu

机构信息

Department of Gastroenterology, Matsushita Memorial Hospital, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan.

出版信息

Gan To Kagaku Ryoho. 2011 Oct;38(10):1705-8.

PMID:21996972
Abstract

A 45-year-old man was admitted to our hospital because of disseminated intravascular coagulation syndrome (DIC) and severe pain in his back and lumbar. Abdominal CT scan demonstrated lymph node enlargement in the whole body. FDG-PET revealed abnormal uptake of FDG in the thickening wall of the descending colon and the entire skeleton. Colonoscopy was performed continuously and revealed a poorly-differentiated adenocarcinoma of the descending colon. He was treated with the systemic chemotherapy of modified FOLFOX6 (mFOLFOX6). After one course of the treatment, DIC was resolved and severe back pain and lumbargo were improved.

摘要

一名45岁男性因弥散性血管内凝血综合征(DIC)以及背部和腰部剧痛入院。腹部CT扫描显示全身淋巴结肿大。氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)显示降结肠增厚壁和整个骨骼中有FDG异常摄取。持续进行结肠镜检查,发现降结肠低分化腺癌。他接受了改良FOLFOX6(mFOLFOX6)全身化疗。经过一个疗程的治疗,DIC得到缓解,严重的背痛和腰痛有所改善。

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