Kubo Naoki, Takeuchi Nobumichi, Nakayama Ataru, Ogiwara Hiroaki, Tsujimoto Kazuo, Ito Norio, Koiwai Keiichiro
Dept. of Surgery, Ina Central Hospital, Japan.
Gan To Kagaku Ryoho. 2011 Apr;38(4):693-5.
A 5 8-year-old man with severe back pain caused by multiple vertebral metastases developed disseminated intravascular coagulation(DIC). We adopted palliative radiotherapy(8 Gy/1 day)for palliation of his back pain as initial treatment. Afterwards, we started sequential chemotherapy consisting of methotrexate(MTX)and 5-fluorouracil(5-FU). After two courses, DIC was resolved, and the patient was discharged in fair condition after five more courses of MTX and 5-FU therapy.
一名58岁男性因多处椎体转移导致严重背痛,并发生了弥散性血管内凝血(DIC)。我们采用姑息性放疗(8 Gy/1天)来缓解其背痛作为初始治疗。之后,我们开始了由甲氨蝶呤(MTX)和5-氟尿嘧啶(5-FU)组成的序贯化疗。两个疗程后,DIC得到缓解,在再进行五个疗程的MTX和5-FU治疗后,患者病情好转出院。