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[采用甲氨蝶呤和5-氟尿嘧啶序贯疗法及姑息性放疗成功治愈源自胃癌的骨髓播散性癌病所致的弥散性血管内凝血]

[Successful withdrawal from disseminated intravascular coagulation caused by disseminated carcinomatosis of bone marrow originated from gastric cancer treated by sequential therapy consisting of MTX and 5-FU and palliative radiotherapy].

作者信息

Kubo Naoki, Takeuchi Nobumichi, Nakayama Ataru, Ogiwara Hiroaki, Tsujimoto Kazuo, Ito Norio, Koiwai Keiichiro

机构信息

Dept. of Surgery, Ina Central Hospital, Japan.

出版信息

Gan To Kagaku Ryoho. 2011 Apr;38(4):693-5.

Abstract

A 5 8-year-old man with severe back pain caused by multiple vertebral metastases developed disseminated intravascular coagulation(DIC). We adopted palliative radiotherapy(8 Gy/1 day)for palliation of his back pain as initial treatment. Afterwards, we started sequential chemotherapy consisting of methotrexate(MTX)and 5-fluorouracil(5-FU). After two courses, DIC was resolved, and the patient was discharged in fair condition after five more courses of MTX and 5-FU therapy.

摘要

一名58岁男性因多处椎体转移导致严重背痛,并发生了弥散性血管内凝血(DIC)。我们采用姑息性放疗(8 Gy/1天)来缓解其背痛作为初始治疗。之后,我们开始了由甲氨蝶呤(MTX)和5-氟尿嘧啶(5-FU)组成的序贯化疗。两个疗程后,DIC得到缓解,在再进行五个疗程的MTX和5-FU治疗后,患者病情好转出院。

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