Gavrisiuk V K, Morskaia N D, Iachnik A I, Morozova N A, Iakhnitsia T V
Kardiologiia. 1990 Mar;30(3):32-5.
In 34 patients with chronic cor pulmonale, the drugs from a group of beta-adrenostimulants, nonachlazinum and oxyphedrinum, were tested for effects on their hemodynamics, pulmonary ventilation function, blood gas composition and acid-base balance. In patients with circulatory failure due to lung diseases, nonachlazinum and oxyphedrinum were found to exert a pronounced positive intropic action, to contribute to an increase in cardiac output. The agents may be included into the multimodality therapy of patients with decompensated chronic cor pulmonale.
对34例慢性肺源性心脏病患者，测试了一组β-肾上腺素能兴奋剂（如非那嗪和麻黄苯丙酮）对其血流动力学、肺通气功能、血气成分及酸碱平衡的影响。在因肺部疾病导致循环衰竭的患者中，发现非那嗪和麻黄苯丙酮具有显著的正性肌力作用，有助于增加心输出量。这些药物可纳入失代偿性慢性肺源性心脏病患者的多模式治疗中。
