Chichkanov G G, Bogolepov A K
Biull Eksp Biol Med. 1978 Dec;86(12):691-4.
In experimental angina pectoris of dogs developed by Sze-keres et al, 1976, and modified by the authors it was shown that nonachlazine in doses of 3 and 5 mg/kg decreased or even completely prevented the ST segment elevation on the epicardial electrogram from the focus of myocardial ischemia. Oxyphedrine in doses of 0.05, 0.1, and 0,3 mg/kg had no such effect. In doses of 0.1 and 0.3 mg/kg the drug aggravated the epicardial electrogram.
在Sze-keres等人于1976年所诱导并经作者改良的犬实验性心绞痛中,结果表明,剂量为3和5mg/kg的农吉利嗪可降低甚至完全防止心肌缺血灶引起的心外膜心电图ST段抬高。剂量为0.05、0.1和0.3mg/kg的去氧麻黄碱则无此作用。剂量为0.1和0.3mg/kg时,该药物会使心外膜心电图恶化。