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[胰腺分裂的临床重要性]

[Clinical importance of pancreas divisum].

作者信息

Herszényi László, Szmola Richárd, Tulassay Zsolt

机构信息

Semmelweis Egyetem, Általános Orvostudományi Kar II. Belgyógyászati Klinika, Budapest.

出版信息

Orv Hetil. 2011 Oct 30;152(44):1764-71. doi: 10.1556/OH.2011.29231.

Abstract

Pancreas divisum, the most common congenital pancreatic anomaly, is associated with three main duct abnormalities: type I, with total failure of fusion; type II, with dorsal duct dominant drainage; and type III, incomplete divisum where a small communication branch is present. Three clinical conditions are associated with pancreas divisum: (1) acute recurrent pancreatitis; (2) chronic pancreatitis with the chronic inflammation in the dorsal bed; (3) abdominal "pancreatic-type" obstructive pain. Endoscopic retrograde cholangiopancreatography is the primary method for diagnosing pancreas divisum, but magnetic resonance cholangiopancreatography is becoming a first choice for non-invasive evaluation. Pancreas divisum per se does not require medical intervention. Patients who experience mild episodic acute pancreatitis should be managed medically. Surgical or endoscopic interventions relieve the obstruction by improving dorsal duct drainage via the minor papilla.

摘要

胰腺分裂是最常见的先天性胰腺异常,与三种主要的导管异常有关:I型,完全融合失败;II型,背侧导管为主的引流;III型,不完全分裂,存在一个小的交通分支。胰腺分裂与三种临床情况相关:(1)急性复发性胰腺炎;(2)伴有背侧床慢性炎症的慢性胰腺炎;(3)腹部“胰腺型”梗阻性疼痛。内镜逆行胰胆管造影是诊断胰腺分裂的主要方法,但磁共振胰胆管造影正成为无创评估的首选。胰腺分裂本身不需要医学干预。经历轻度发作性急性胰腺炎的患者应进行药物治疗。手术或内镜干预通过改善经小乳头的背侧导管引流来缓解梗阻。

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