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胰腺分裂与胰腺炎:一种偶然的关联?

Pancreas divisum and pancreatitis: a coincidental association?

作者信息

Burtin P, Person B, Charneau J, Boyer J

机构信息

Service d'Hepatogastroenterologie, Centre Hospitalier Universitaire, Angers, France.

出版信息

Endoscopy. 1991 Mar;23(2):55-8. doi: 10.1055/s-2007-1010612.

Abstract

The aim of the present study is to assess the frequency of pancreas divisum and the features of patients with pancreas divisum in order to assess the role of this anomaly in the occurrence of pancreatitis. A total of 1049 endoscopic retrograde pancreatographies were studied between 1978 and 1988. Patients with pancreas divisum were studied in terms of their clinical findings and their disease (pancreatitis or not). Pancreas divisum was diagnosed in 62 patients (5.9%). No statistical differences with regard to age and sex were found between patients with and without pancreas divisum. The frequency of pancreas divisum was similar in the different groups of disease, especially chronic pancreatitis, acute pancreatitis, recurrent pancreatitis and idiopathic pancreatitis. The study of pancreatograms showed that dorsal ductal abnormalities alone were found as frequently as ventral alterations alone. Our results show that pancreas divisum cannot be directly implicated in the occurrence of pancreatitis, and should not prompt a systematic sphincterotomy of the accessory papilla. This treatment should only be considered in the rare cases of acute recurrent idiopathic pancreatitis with dorsal ductal dilatation and stenosis of the accessory papilla.

摘要

本研究的目的是评估胰腺分裂的发生率以及胰腺分裂患者的特征,以便评估这种异常在胰腺炎发生中的作用。1978年至1988年间共研究了1049例内镜逆行胰胆管造影术。对胰腺分裂患者的临床发现和疾病情况(是否患有胰腺炎)进行了研究。62例患者(5.9%)被诊断为胰腺分裂。胰腺分裂患者与非胰腺分裂患者在年龄和性别方面未发现统计学差异。胰腺分裂在不同疾病组中的发生率相似,尤其是慢性胰腺炎、急性胰腺炎、复发性胰腺炎和特发性胰腺炎。胰胆管造影研究表明,单独发现背侧导管异常的频率与单独发现腹侧改变的频率相同。我们的结果表明,胰腺分裂不能直接与胰腺炎的发生相关,并且不应促使对副乳头进行系统性括约肌切开术。这种治疗仅应在罕见的急性复发性特发性胰腺炎伴有背侧导管扩张和副乳头狭窄的情况下考虑。

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