Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul 138-736, Korea.
Radiology. 2012 Jan;262(1):335-42. doi: 10.1148/radiol.11110416. Epub 2011 Oct 13.
To evaluate clinical aspects and imaging features of complications encountered in the treatment of benign thyroid nodules with radiofrequency (RF) ablation.
Institutional review board approval was obtained for this retrospective study, and informed consent was waived. From June 2002 to September 2009, 1459 patients underwent RF ablation of 1543 thyroid nodules with an RF system with internally cooled electrodes at 13 thyroid centers, which were members of Korean Society of Thyroid Radiology. Numbers and types of major and minor complications were assessed.
The authors observed 48 complications (3.3%), 20 major and 28 minor. The major complications were voice changes (n = 15), brachial plexus injury (n = 1), tumor rupture (n = 3), and permanent hypothyroidism (n = 1). The minor complications were hematoma (n = 15), skin burn (n = 4), and vomiting (n = 9). All patients recovered spontaneously except for one with permanent hypothyroidism and one who underwent surgery.
Although the complication rate of RF ablation is low, various complications may occur; comprehension of complications and suggested technical tips may prevent complications or properly manage those that occur.
评估射频（RF）消融治疗良性甲状腺结节的并发症的临床和影像学特征。
本回顾性研究获得了机构审查委员会的批准，并豁免了知情同意。2002 年 6 月至 2009 年 9 月，在 13 个甲状腺中心（均为韩国甲状腺放射学会成员），1459 名患者使用具有内部冷却电极的 RF 系统对 1543 个甲状腺结节进行了 RF 消融。评估了主要和次要并发症的数量和类型。
作者观察到 48 种并发症（3.3%），其中 20 种为主要并发症，28 种为次要并发症。主要并发症包括声音改变（n = 15）、臂丛神经损伤（n = 1）、肿瘤破裂（n = 3）和永久性甲状腺功能减退（n = 1）。次要并发症包括血肿（n = 15）、皮肤烧伤（n = 4）和呕吐（n = 9）。除 1 例永久性甲状腺功能减退和 1 例手术患者外，所有患者均自行恢复。
虽然 RF 消融的并发症发生率较低，但可能会发生各种并发症；了解并发症和建议的技术要点可以预防并发症或妥善处理发生的并发症。
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