BC Children's Hospital, Department of Pediatrics, Vancouver, BC, Canada.
Can Fam Physician. 2011 Oct;57(10):1134-6.
I prescribe oral steroids for children in my community when they suffer asthma exacerbation. How many doses of steroids are recommended? Do all children need to take steroids for 5 days?
Traditionally, mild-to-moderate pediatric asthma exacerbations have been treated with a short course of oral steroids-often 5 days of prednisone or prednisolone. However, recent evidence suggests a similar outcome can be acheived with a single dose of dexamethasone, which has a longer half-life and powerful anti-inflammatory effects, along with easier administration and compliance. Single-dose dexamethasone offers a simple and reliable treatment for these patients in office, urgent care, and emergency department settings.
当我的社区儿童哮喘发作时，我会给他们开口服类固醇。建议使用多少剂量的类固醇？所有儿童都需要服用 5 天的类固醇吗？
传统上，轻度至中度儿童哮喘发作采用短期口服类固醇治疗-通常为 5 天泼尼松或泼尼松龙。然而，最近的证据表明，单次给予地塞米松也可以达到类似的效果，地塞米松半衰期更长，具有强大的抗炎作用，且给药和顺应性更简单。单剂量地塞米松为这些在诊所、紧急护理和急诊科就诊的患者提供了一种简单可靠的治疗方法。
