Najafi Sh, Tohidastakrad Z, Momenbeitollahi J
Assistant Professor, Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
J Dent (Tehran). 2011 Winter;8(1):39-43. Epub 2011 Mar 31.
The improvement in survival and local control measures in children with neoplasm in the head and neck region may lead to increased iatrogenic adverse effects of treatment. The aim of this study was to report a new case of the long-term effects of chemoradiotherapy on oral health and dental development in a patient treated for Hodgkin's disease at an early age. In this case report, a 26-year-old female is presented, who at the age of 5 years received chemotherapy and radiotherapy for Hodgkin's disease in the neck region. The patient consulted the Department of Oral Medicine because of dental changes and tooth loss despite adequate dental care and oral hygiene. Clinical examination revealed loose teeth and inflamed gingiva of the mandible, x-ray showed premature root resorption, V-shaped and shortened roots and alveolar bone loss. After examination, the patient was referred for extracting the mandibular teeth and then wassent to the prosthetics department. Therefore, in order to decrease dental treatment sequelae in patients who have had cured malignant disease, these cases should have life-long dental care and follow-up.
头颈部肿瘤患儿生存及局部控制措施的改善可能会导致治疗的医源性不良反应增加。本研究的目的是报告一例早年接受霍奇金病治疗的患者放化疗对口腔健康和牙齿发育长期影响的新病例。在本病例报告中，介绍了一名26岁女性，她5岁时因颈部霍奇金病接受了化疗和放疗。尽管患者有足够的牙齿护理和口腔卫生，但因牙齿变化和牙齿脱落就诊于口腔医学科。临床检查发现下颌牙齿松动、牙龈发炎，X线显示牙根过早吸收、V形根和牙根缩短以及牙槽骨丧失。检查后，患者被转诊拔除下颌牙齿，然后被送往修复科。因此，为了减少已治愈恶性疾病患者的牙科治疗后遗症，这些病例应接受终身牙齿护理和随访。
