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干细胞倡导中的创新:有衡量才有收获。

Innovation in stem cell advocacy: you only get what you can measure.

机构信息

Sidley Austin LLP, 787 Seventh Avenue, NY 10019, USA.

出版信息

Regen Med. 2011 Nov;6(6 Suppl):127-32. doi: 10.2217/rme.11.72.

Abstract

We propose that stem cell advocacy must engage in self-analysis to determine how to be maximally effective. For this analysis, eight advocacy elements can be measured: agitation, legislation, regulation, litigation, policy development, collaboration, education and innovation. For several of these elements, we show that stem cell advocates, particularly advocates for human embryonic stem cell research, have been matched by their opponents. This demonstrates the need for combining innovation and collaboration with advocacy-oriented education. To pursue innovative and collaborative education, we propose a 'bench-to-public knowledge' model and present some preliminary observations made with this model for different stem cell types. We also propose development of a semantic web information system to be operated within Internet Cloud/Apps/Social Media. We call this system the 'Stem Cell Information Technology Accelerator Platform'. Toward its construction, we propose formation of a working group to conceive semantic web ontology for stem cell science and its clinical translation into medicine. This ontology would function as a map of the relationships between and among the various informational components comprising discourse on stem cell research and its clinical translation, and would allow various stakeholders to contribute to evolving models of that science and translation. These models could, in turn, support an innovative and collaborative approach to education in furtherance of stem cell advocacy.

摘要

我们提出,干细胞倡导必须进行自我分析,以确定如何才能最大限度地发挥作用。为此,可以衡量八项倡导要素:鼓动、立法、监管、诉讼、政策制定、合作、教育和创新。对于其中的几个要素,我们表明,干细胞倡导者,特别是人类胚胎干细胞研究的倡导者,已经与他们的对手相匹配。这表明需要将创新和合作与面向倡导的教育相结合。为了追求创新和协作教育,我们提出了一个“从实验室到公众知识”的模型,并提出了一些用这个模型对不同类型的干细胞进行初步观察的结果。我们还建议开发一个语义网络信息系统,在互联网云/应用程序/社交媒体中运行。我们称这个系统为“干细胞信息技术加速器平台”。为了实现其建设,我们建议成立一个工作组,构思干细胞科学及其临床转化为医学的语义网络本体论。这个本体论将作为一个描述符,描述干细胞研究及其临床转化的各个信息组成部分之间的关系,使不同的利益相关者能够为该科学及其转化的发展模式做出贡献。这些模型反过来又可以支持一种创新和协作的教育方法,以促进干细胞倡导。

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