来自 D. harmsiana Engl.（桑科）的羽扇豆醇长链烷酸酯。

Long-chain alkanoic acid esters of lupeol from Dorstenia harmsiana Engl. (Moraceae).

机构信息

Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, PO Box 812, Yaoundé, Cameroon.

出版信息

Nat Prod Res. 2012;26(8):749-55. doi: 10.1080/14786419.2010.551769. Epub 2011 Oct 14.

DOI:10.1080/14786419.2010.551769

PMID:21999356

Abstract

In addition to lupeol (1a), three long-chain alkanoic acid esters of lupeol, in which two were new, were isolated from the hexane and ethyl acetate twigs extract of Dorstenia harmsiana Engl. (Moraceae). The structures of the new compounds were elucidated on the basis of 1D and 2D NMR experiments. Some isolated compounds were evaluated for their antimicrobial activities. The lupeol and its three long-chain alkanoic acid esters showed antifungal and antibacterial activities.

摘要

除了羽扇豆醇（1a）之外，还从肾茶 Dorstenia harmsiana Engl.（桑科）的正己烷和乙酸乙酯枝叶提取物中分离出三种羽扇豆醇的长链烷酸酯，其中两种为新化合物。根据 1D 和 2D NMR 实验确定了新化合物的结构。对一些分离得到的化合物进行了抗菌活性评价。羽扇豆醇及其三种长链烷酸酯具有抗真菌和抗菌活性。