新型抗菌药物。何时是最佳选择，何时并非如此。

The new antimicrobial agents. When they're the best choice and when they're not.

作者信息

Rey A M, Gums J G, Grauer K

机构信息

Family Practice Medical Group, Gainesville, FL 32601.

出版信息

Postgrad Med. 1990 Aug;88(2):64-8, 71-3, 77-81. doi: 10.1080/00325481.1990.11704697.

DOI:10.1080/00325481.1990.11704697

PMID:2199959

Abstract

The number of antibiotics available to the clinician for treatment of infectious diseases continues to increase. However, choosing an agent just because it is new is not always cost-effective and may encourage the development of bacterial resistance. The site of infection, pharmacokinetic data, minimum inhibitory concentration, and cost must all be considered in selecting the optimal antimicrobial agent for a particular clinical situation.

摘要

临床医生可用于治疗传染病的抗生素数量持续增加。然而，仅仅因为一种药物是新药就选择它并不总是具有成本效益的，而且可能会助长细菌耐药性的发展。在为特定临床情况选择最佳抗菌药物时，必须考虑感染部位、药代动力学数据、最低抑菌浓度和成本等所有因素。