Thieman Kelley M, Kirkby Kristin A, Flynn-Lurie Alison, Grooters Amy M, Bacon Nicholas J
Department of Small Animal Clinical Sciences, Veterinary Medical Center, College of Veterinary Medicine, University of Florida, Gainesville, 32611, USA.
J Am Vet Med Assoc. 2011 Nov 1;239(9):1232-5. doi: 10.2460/javma.239.9.1232.
A 4-year-old spayed female Boxer was evaluated for a cutaneous mass located on the dorsum. The mass had been present for 6 weeks and was increasing in size.
A mass of approximately 10 cm in diameter was detected on the dorsum cranial to the right ilial wing. Histologic examination of a tissue sample from the mass led to the diagnosis of cutaneous pythiosis. Computed tomography of the abdomen and the mass were performed and revealed a contrast-enhancing soft tissue mass of the dorsum and enlarged intra-abdominal lymph nodes.
The dog underwent surgical excision of the cutaneous mass, including 5-cm skin margins and deep margins of 2 fascial planes. The mass was completely excised on the basis of results of histologic examination of surgical margins. The dog received itraconazole and terbinafine by mouth for 3 months following surgery. Recheck examination at 20 months postoperatively showed no signs of recurrence of pythiosis at the surgical site.
Aggressive surgical excision in combination with medical treatment resulted in a favorable long-term (> 1 year) outcome in this dog. Thorough workup including diagnostic imaging and lymph node evaluation is recommended. If surgery is to be performed, skin margins of 5 cm and deep margins of 2 fascial planes are recommended.
一只4岁已绝育的雌性拳师犬因背部出现皮肤肿物而接受评估。该肿物已存在6周，且在不断增大。
在右髂骨翼上方的背部检测到一个直径约10厘米的肿物。对肿物组织样本进行组织学检查后诊断为皮肤芽生菌病。对腹部和肿物进行了计算机断层扫描，结果显示背部有一个强化的软组织肿物以及腹腔内淋巴结肿大。
这只犬接受了皮肤肿物的手术切除，包括5厘米的皮肤切缘和2个筋膜平面的深部切缘。根据手术切缘的组织学检查结果，肿物被完全切除。术后这只犬口服伊曲康唑和特比萘芬3个月。术后20个月的复查显示手术部位没有皮肤芽生菌病复发的迹象。
在这只犬中，积极的手术切除联合药物治疗取得了良好的长期（>1年）效果。建议进行包括诊断性影像学检查和淋巴结评估在内的全面检查。如果要进行手术，建议皮肤切缘为5厘米，深部切缘为2个筋膜平面。
