Institute of Molecular Biosciences, Structural Biology, University of Graz, Graz, Austria.
Prog Mol Biol Transl Sci. 2011;103:73-130. doi: 10.1016/B978-0-12-415906-8.00004-2.
S-layers are self-assembled paracrystalline protein lattices that cover many bacteria and almost all archaea. As an important component of the bacterial cell envelope, S-layers can fulfill various biological functions and are usually the most abundantly expressed protein species in a cell. Here we review the structures of the best characterized S-layer proteins from Gram-positive and Gram-negative bacteria, as well as methods to determine their molecular architecture.
S- 层是自我组装的准晶蛋白晶格，覆盖着许多细菌和几乎所有的古菌。作为细菌细胞包膜的重要组成部分，S- 层可以发挥各种生物学功能，通常是细胞中表达最丰富的蛋白质种类。在这里，我们综述了革兰氏阳性菌和革兰氏阴性菌中研究最为透彻的 S- 层蛋白的结构，以及确定其分子结构的方法。
