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[The study of protein-peptide hormones using genetic engineering methods (review of the literature)].

作者信息

Mertvetsov N P, Karginov V A

出版信息

Vopr Med Khim. 1990 May-Jun;36(3):2-13.

PMID:2200204
Abstract

Use of genetic engineering technique in cloning and sequence assay of cDNA and genes coding for mammal protein and peptide hormones is reviewed. Recent data on molecular aspects of gene reorganization in some inherited disorders are considered involving analytical methods for evaluation of gene activity, especially of genes coding for peptide hormones. Sequence assay of mRNA coding for mammal proopiomelanocortins (precursor of adrenocorticotropic hormone), beta-lipotropic hormones of pituitary body, is discussed.

摘要

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