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粪便血红蛋白、白蛋白和α-1-抗胰蛋白酶在检测胃肠道出血中的实用性。

The usefulness of faecal haemoglobin, albumin and alpha-1-antitrypsin in the detection of gastrointestinal bleeding.

作者信息

Morrow R J, Lawson N, Hussaini S H, Asquith P

机构信息

Department of Clinical Chemistry, East Birmingham Hospital, Bordesley Green East, UK.

出版信息

Ann Clin Biochem. 1990 May;27 ( Pt 3):208-12. doi: 10.1177/000456329002700305.

Abstract

A pilot study was undertaken to find out whether faecal haemoglobin, albumin and alpha-1-antitrypsin from patients with gastrointestinal disorders could distinguish active bleeders from non-active bleeders and healthy volunteers. Alpha-1-antitrypsin is not as readily degraded by endogenous and bacterial breakdown as haemoglobin and albumin and consequently could be a better marker for occult bleeding.

摘要

开展了一项初步研究,以确定胃肠道疾病患者的粪便血红蛋白、白蛋白和α-1抗胰蛋白酶能否区分活动性出血者与非活动性出血者以及健康志愿者。与血红蛋白和白蛋白相比,α-1抗胰蛋白酶不易被内源性和细菌分解所降解,因此可能是隐匿性出血的更好标志物。

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