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柔性壁弯曲动脉生物力学行为的流固耦合研究

A fluid?structure interaction study on the biomechanical behaviour of a curved artery with flexible wall.

作者信息

Wang Xiaohong, Li Xiaoyang

机构信息

Biomechanical Research Laboratory, College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, No. 100 Pingleyuan, Chaoyang District, Beijing, PR China.

出版信息

J Med Eng Technol. 2011 Nov;35(8):402-9. doi: 10.3109/03091902.2011.619625. Epub 2011 Oct 17.

Abstract

Research has shown that thrombus, stenosis, aneurysm, atherosclerosis and other vascular diseases are likely to occur in curved arteries such as aortic arch, coronary artery and cerebral artery. It is found that fatigue damage and failure of arteries are closely associated with the dynamic physiological environment where the arteries are situated. Based on these considerations, the behaviour of curved arteries subjected to a physiological environment is presented in this paper. The fluid-structure interaction (FSI) effect is considered. Wall stress distribution and its variation over time are investigated. Artery deformation regularity throughout the cardiac cycle has been analysed. It is believed that this study may provide insights into clinical research in the future.

摘要

研究表明,血栓、狭窄、动脉瘤、动脉粥样硬化等血管疾病很可能发生在诸如主动脉弓、冠状动脉和脑动脉等弯曲动脉中。研究发现,动脉的疲劳损伤和失效与动脉所处的动态生理环境密切相关。基于这些考虑,本文阐述了处于生理环境下弯曲动脉的行为。考虑了流固耦合(FSI)效应。研究了壁面应力分布及其随时间的变化。分析了整个心动周期中动脉变形规律。相信该研究可为未来的临床研究提供见解。

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