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高级别浸润性尿路上皮癌伴局灶浆细胞样分化，经尿道电切术联合放化疗治疗后成功。

High-grade invasive urothelial carcinoma with focal plasmacytoid differentiation successfully treated by transurethral resection followed by chemoradiotherapy.

机构信息

Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.

出版信息

Int J Urol. 2011 Dec;18(12):851-3. doi: 10.1111/j.1442-2042.2011.02880.x. Epub 2011 Oct 17.

DOI:10.1111/j.1442-2042.2011.02880.x
PMID:22004222
Abstract

We report a case of high-grade invasive urothelial carcinoma with plasmacytoid differentiation of the urinary bladder. A 75-year-old woman was referred to our hospital because of macroscopic hematuria. Cystoscopy detected a solid pedunculated bladder tumor, and a transurethral resection of the bladder tumor (TUR-Bt) and the image findings showed pT1N0M0 bladder cancer. The histopathological examination revealed the coexistence of a large component of high-grade invasive urothelial carcinoma and a small component of plasmacytoid carcinoma. Following the TUR-Bt, external beam radiotherapy and chemotherapy with gemcitabine and nedaplatin were carried out. The bladder tumor has not recurred for 2 years after the TUR-Bt.

摘要

我们报告一例膀胱高级别浸润性尿路上皮癌伴浆母细胞分化。一名 75 岁女性因肉眼血尿被转至我院。膀胱镜检查发现一实性有蒂膀胱肿瘤，行经尿道膀胱肿瘤切除术（TUR-Bt），影像学检查显示膀胱癌 pT1N0M0 期。组织病理学检查显示存在大比例的高级别浸润性尿路上皮癌和小比例的浆母细胞瘤。TUR-Bt 后，行吉西他滨和顺铂化疗联合外照射放疗。TUR-Bt 后 2 年内膀胱肿瘤未复发。

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Am J Case Rep. 2020 Jul 9;21:e923130. doi: 10.12659/AJCR.923130.
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Organ-confined plasmacytoid urothelial carcinoma: implication of the lack of expression of the receptor tyrosine kinase MET.器官局限性浆细胞样尿路上皮癌：受体酪氨酸激酶MET表达缺失的意义
Int J Clin Exp Pathol. 2018 Mar 1;11(3):1754-1757. eCollection 2018.
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A Low Psoas Muscle Index before Treatment Can Predict a Poorer Prognosis in Advanced Bladder Cancer Patients Who Receive Gemcitabine and Nedaplatin Therapy.
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Pretreatment Neutrophil-to-Lymphocyte Ratio Can Predict the Prognosis in Bladder Cancer Patients Who Receive Gemcitabine and Nedaplatin Therapy.治疗前中性粒细胞与淋巴细胞比值可预测接受吉西他滨和顺铂治疗的膀胱癌患者的预后。
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