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Holford NHG and Sheiner LB "Understanding the Dose-Effect Relationship-Clinical Application of Pharmacokinetic-Pharmacodynamic Models", Clin Pharmacokin 6:429-453 (1981)-The Backstory.

作者信息

Holford Nick

机构信息

Clinical Pharmacology, University of Auckland, New Zealand.

出版信息

AAPS J. 2011 Dec;13(4):662-4. doi: 10.1208/s12248-011-9306-5. Epub 2011 Oct 18.

Abstract
摘要

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Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models.
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