太白贝母中的三种新甾体皂苷。

Three new steroidal saponins from Fritillaria pallidiflora.

作者信息

Shen Shuo, Chen Chao-Jun, Bu Ren, Ga Lu, Li Guo-Yu, Tan Yong, Li Xian, Wang Jin-Hui

机构信息

School of Pharmacy, Inner Monglia Medical College, Hohhot, 010110, China.

出版信息

J Asian Nat Prod Res. 2011 Oct;13(11):1014-22. doi: 10.1080/10286020.2011.619979. Epub 2011 Oct 19.

DOI:10.1080/10286020.2011.619979

PMID:22008065

Abstract

Three new steroidal saponins, pallidiflosides A (1), B (2), and C (3), have been isolated from the dry bulbs of Fritillaria pallidiflora Schrenk. Their structures were elucidated as 26-O-β-d-glucopyranosyl-(25R)-furost-5,20(22)-dien-3β,26-diol-3-O-β-d-xylopyranosyl(1 → 4)-[α-l-rhamnopyranosyl(1 → 2)]-β-d-glucopyranoside (1); 26-O-β-d-glucopyranosyl-3β,26-dihydroxyl-20,22-seco-25(R)-furost-5-en-20,22-dione-3-O-α-l-rhamnopyranosyl(1 → 2)-β-d-glucopyranoside (2); and (25R)-spirost-5-ene-3β,17α-diol-3-O-β-d-glucopyranosyl(1 → 4)-β-d-galactopyranoside (3) by spectroscopic techniques and chemical means.

摘要

从伊犁贝母干燥鳞茎中分离得到3个新的甾体皂苷，即伊犁贝母苷A（1）、B（2）和C（3）。通过光谱技术和化学方法确定它们的结构分别为26 - O - β - D - 吡喃葡萄糖基 - (25R) - 呋甾 - 5,20(22) - 二烯 - 3β,26 - 二醇 - 3 - O - β - D - 吡喃木糖基(1→4) - [α - L - 吡喃鼠李糖基(1→2)] - β - D - 吡喃葡萄糖苷（1）；26 - O - β - D - 吡喃葡萄糖基 - 3β,26 - 二羟基 - 20,22 - 断 - 25(R) - 呋甾 - 5 - 烯 - 20,22 - 二酮 - 3 - O - α - L - 吡喃鼠李糖基(1→2) - β - D - 吡喃葡萄糖苷（2）；以及(25R) - 螺旋甾 - 5 - 烯 - 3β,17α - 二醇 - 3 - O - β - D - 吡喃葡萄糖基(1→4) - β - D - 吡喃半乳糖苷（3）。