Hoffmann M, Geldner G, Leschke M
Klinik für Anästhesie, Intensivmedizin, Schmerztherapie und Notfallmedizin, Klinikum Ludwigsburg.
Dtsch Med Wochenschr. 2011 Oct;136(43):2192-5. doi: 10.1055/s-0031-1292031. Epub 2011 Oct 18.
A 28-year-old male patient with sickle cell disease developed a vasoocclusive crisis with an acute chest syndrome and severe lung failure.
After partial substitution transfusion the patient was successfully treated extracorporeal membrane oxygenation (ECMO). After 12 days he was weaned from the ECMO, 2 days later the patient's tracheostoma was removed. 19 days after the event the patient had recovered completely and was moved to a hospital in Paris from where he came.
Apparently data is sparse regarding the use of ECMO for treatment of a life-threatening acute chest syndrome in sickle cell disease. However, the therapy approach seems to be promising and is worth considering in this particular situation.
一名28岁患有镰状细胞病的男性患者发生血管闭塞性危机,伴有急性胸部综合征和严重肺衰竭。
在进行部分置换输血后,患者成功接受了体外膜肺氧合(ECMO)治疗。12天后,他脱离了ECMO,2天后患者的气管造口被移除。事件发生19天后,患者已完全康复,并被转回他来自的巴黎的一家医院。
显然,关于使用ECMO治疗镰状细胞病危及生命的急性胸部综合征的数据很少。然而,这种治疗方法似乎很有前景,在这种特殊情况下值得考虑。