Jovito Vanessa C, Freires Irlan A, Almeida Leopoldina F D, Moura Douglas, Castro Ricardo D, Paulo Marçal Q, Leite-Cavalcanti Alessandro
Department of Clinics and Social Dentistry, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.
Acta Odontol Latinoam. 2011;24(1):41-6.
The aim of this study was to evaluate the in vitro activity of dentifrices containing the hydroalcoholic extract of the ripe fruit of Eugenia uniflora L. (Surinam cherry) on Streptococcus oralis (ATCC 10557) and Lactobacillus casei (ATCC 7469). Five dentifrices were used: D1: containing hydroalcoholic extract of Eugenia uniflora L.; D2: containing fluoride and hydroalcoholic extract of Eugenia uniflora L.; D3: containing triclosan and hydroalcoholic extract of Eugenia uniflora L; D4: containing triclosan, fluoride and hydroalcoholic extract of Eugenia uniflora L.; D5: positive control (Colgate Total 12). To determine the antibacterial activity, the technique used was the minimum inhibitory concentration by the diffusion method in solid culture medium. At the concentration 0.05 g/mL, the best results were achieved with D1 (18 mm) and D4 (24 mm) on L.casei, and with D3 (19 mm) on S. oralis. The dentifrices D3 and D4 were found to have greater activity on the Streptococcus oralis, while D4 and D1 were found to have greater activity on Lactobaccilus casei. It is concluded that dentifrices with Eugenia uniflora L. have antimicrobial activity, suggesting that clinical trials should be conducted.
本研究的目的是评估含有 Eugenia uniflora L.（苏里南樱桃）成熟果实水醇提取物的牙膏对口腔链球菌（ATCC 10557）和干酪乳杆菌（ATCC 7469）的体外活性。使用了五种牙膏：D1：含有 Eugenia uniflora L. 的水醇提取物；D2：含有氟化物和 Eugenia uniflora L. 的水醇提取物；D3：含有三氯生和 Eugenia uniflora L. 的水醇提取物；D4：含有三氯生、氟化物和 Eugenia uniflora L. 的水醇提取物；D5：阳性对照（高露洁全效 12）。为了确定抗菌活性，采用的技术是固体培养基扩散法的最低抑菌浓度。在浓度为 0.05 g/mL 时，D1（18 mm）和 D4（24 mm）对干酪乳杆菌的效果最佳，D3（19 mm）对口腔链球菌的效果最佳。发现牙膏 D3 和 D4 对口腔链球菌的活性更强，而 D4 和 D1 对干酪乳杆菌的活性更强。结论是含有 Eugenia uniflora L. 的牙膏具有抗菌活性，建议进行临床试验。
