Mahmoud Mohamad S
Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University Women's Healthcare, 1200 East Michigan Avenue, Suite 700, Lansing, MI 48912, USA.
J Reprod Med. 2011 Sep-Oct;56(9-10):405-9.
Bladder pain syndrome--formally known as interstitial cystitis--is a chronic bladder disorder characterized by pelvic pain and urinary irritability symptoms. The physiopathology is still unclear but is thought to involve bladder mucosal injury, inflammation and neurologic dysfunction. It is hard to diagnose this entity due to symptoms that are common to several other pathologies such as chronic pelvic pain, endometriosis, overactive bladder, urinary tract infection, and vulvodynia, and due to the lack of specific findings. A combination of history, physical examination, and diagnostic tools helps the establishment of the diagnosis by ruling out other similar pathologies. Treatment is multimodal and combines behavioral changes, drugs administered orally or intravesically and even surgery for refractory cases.
膀胱疼痛综合征——以前称为间质性膀胱炎——是一种慢性膀胱疾病，其特征为盆腔疼痛和排尿刺激症状。其生理病理学仍不清楚，但被认为涉及膀胱黏膜损伤、炎症和神经功能障碍。由于该疾病的症状与其他几种病症（如慢性盆腔疼痛、子宫内膜异位症、膀胱过度活动症、尿路感染和外阴痛）常见的症状相同，且缺乏特异性发现，因此很难诊断。病史、体格检查和诊断工具相结合，通过排除其他类似病症有助于确诊。治疗是多模式的，包括行为改变、口服或膀胱内给药，甚至对难治性病例进行手术。
