Ghanim Nibal, Alchyib Omrou, Morrish Donald, Tompkins David, Julliard Kell, Visconti Ernest, Hoskins Iffath A
Department of Obstetrics and Gynecology, Lutheran Medical Center, 150 55th Street, Brooklyn, NY 11220, USA.
J Reprod Med. 2011 Sep-Oct;56(9-10):421-4.
To estimate prevalence of rectovaginal colonization by Staphylococcus aureus among pregnant women with group B streptococcus (GBS) screening results and its association with maternal and infant outcomes.
Cultures that detected both group B streptococcus (GBS) and S. aureus were obtained at > or = 35 weeks of gestation. Computerized database search and chart review determined invasive neonatal infection and maternal outcomes at the time of delivery through 6 months postpartum.
A total of 6,626 GBS screening cultures met study criteria, and 769 (11.6%) GBS isolates and 67 (1.0%) S. aureus were identified. No maternal S. aureus-related outcomes were found. The rate of maternal methicillin-resistant S. aureus colonization was 0.1% (7 in 6,626). GBS-positive patients were twice as likely to be colonized with methicillin-susceptible S. aureus than GBS-negative patients. GBS-positive culture rates differed significantly by primary language: Spanish 10.0%, English 13.7%, Russian 26.9%, Cantonese 13.2%, Mandarin 11.5%, Arabic 15.9%, and other 17.8%.
In our population, S. aureus colonization percentage (1.0%) was lower than the 7.5-8.2% reported by other medical centers, as was overall GBS carriage rate. S. aureus did not predispose to maternal or infant morbidity or mortality up to 6 months postpartum.
评估B族链球菌（GBS）筛查结果呈阳性的孕妇中金黄色葡萄球菌直肠阴道定植的患病率及其与母婴结局的关联。
在妊娠≥35周时获取同时检测出B族链球菌（GBS）和金黄色葡萄球菌的培养物。通过计算机数据库检索和病历审查确定分娩时及产后6个月内的新生儿侵袭性感染和母亲结局。
共有6626份GBS筛查培养物符合研究标准，鉴定出769株（11.6%）GBS分离株和67株（1.0%）金黄色葡萄球菌。未发现与母亲金黄色葡萄球菌相关的结局。母亲耐甲氧西林金黄色葡萄球菌定植率为0.1%（6626例中有7例）。GBS阳性患者被甲氧西林敏感金黄色葡萄球菌定植的可能性是GBS阴性患者的两倍。GBS阳性培养率因主要语言不同而有显著差异：西班牙语为10.0%，英语为13.7%，俄语为26.9%，粤语为13.2%，普通话为11.5%，阿拉伯语为15.9%，其他为17.8%。
在我们的研究人群中，金黄色葡萄球菌定植率（1.0%）低于其他医疗中心报告的7.5 - 8.2%，总体GBS携带率也是如此。在产后6个月内，金黄色葡萄球菌并未导致母亲或婴儿发病或死亡。
