Women's and Children's Program, Providence St. Vincent Medical Center, Portland, Oregon, USA.
Am J Perinatol. 2011 Oct;28(9):673-6. doi: 10.1055/s-0031-1276732. Epub 2011 May 3.
We sought to determine the rate of Staphylococcus aureus rectovaginal colonization and positive newborn blood cultures. Routinely obtained group B streptococcus (GBS) rectovaginal specimens were cultured for S. aureus using standard microbiology procedures. S. aureus- and GBS-positive blood cultures in infants less than 3 days old were determined from our microbiology database. Overall, 1488 rectovaginal cultures were obtained. Rates of positive GBS, S. aureus, and methicillin-resistant S. aureus (MRSA) cultures were 20.2%, 8.2%, and 1.7%, respectively. Cultures were positive for methicillin-susceptible S. aureus (MSSA) and GBS or MRSA and GBS in 1.6% and 0.3% of women, respectively. There was no association between GBS and MSSA or MRSA. From 1998 to 2008, there were four positive S. aureus blood cultures (0.4/10,000 live births). The rate of early onset GBS-positive blood cultures was 2.8/10,000 live births. S. aureus rectovaginal colonization at 35 to 37 weeks is relatively uncommon and currently does not appear to pose a significant risk of early onset neonatal sepsis.
我们旨在确定金黄色葡萄球菌直肠阴道定植和新生儿血培养阳性的发生率。常规采集 B 组链球菌（GBS）直肠阴道标本，采用标准微生物学方法培养金黄色葡萄球菌。从我们的微生物数据库中确定出生不到 3 天的婴儿金黄色葡萄球菌和 GBS 阳性血培养的情况。总共获得了 1488 例直肠阴道培养物。GBS、金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌（MRSA）培养阳性率分别为 20.2%、8.2%和 1.7%。分别有 1.6%和 0.3%的女性的培养物呈金黄色葡萄球菌（MSSA）和 GBS 或 MRSA 和 GBS 阳性。GBS 与 MSSA 或 MRSA 之间没有关联。1998 年至 2008 年，有 4 例金黄色葡萄球菌血培养阳性（0.4/10000 活产）。早发型 GBS 阳性血培养的发生率为 2.8/10000 活产。35 至 37 周时金黄色葡萄球菌直肠阴道定植相对少见，目前似乎不会对早发型新生儿败血症构成重大风险。
