Department of Dermatology, Shiga University of Medical Science, Shiga, Japan.
J Dermatol. 2012 May;39(5):466-9. doi: 10.1111/j.1346-8138.2011.01393.x. Epub 2011 Oct 20.
Although disseminated nocardiosis has been increasing with the expansion of immunosuppressive therapy and improvement in diagnostic methods, muscle abscess is a rare complication. There have been only nine case reports of muscle abscess due to Nocardia infection in the English-language published work. We present a case of muscle abscess with disseminated nocardiosis, and review the published work. The patient had been taking prednisolone at 20 mg a day for autoimmune hemolytic anemia for 14 years. She presented with erythema on her thigh resembling cellulitis. Computed tomography showed muscle abscess. The isolated organism was identified as Nocardia farcinica employing polymerase chain reaction and antibiotic sensitivity testing. The diagnosis of muscle abscess due to nocardiosis can be easily missed because there are no characteristic symptoms.
虽然随着免疫抑制治疗的扩大和诊断方法的改进，播散性诺卡氏菌病的发病率一直在增加，但肌肉脓肿是一种罕见的并发症。在英文已发表的文献中，仅有 9 篇关于诺卡氏菌感染导致肌肉脓肿的病例报告。我们报告了一例播散性诺卡氏菌病伴肌肉脓肿，并复习了已发表的文献。患者因自身免疫性溶血性贫血每天服用 20 毫克泼尼松龙已 14 年。她大腿上出现红斑，类似于蜂窝织炎。计算机断层扫描显示肌肉脓肿。采用聚合酶链反应和抗生素敏感性试验，分离出的病原体为星形诺卡氏菌。由于没有特征性症状，因此很容易漏诊由诺卡氏菌引起的肌肉脓肿。
