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From bedside to bench and back: perfecting lipid emulsion therapy for local anesthetic toxicity.从床边到实验室再回归临床：完善用于局部麻醉药中毒的脂质乳剂治疗法
Anesthesiology. 2011 Dec;115(6):1151-2. doi: 10.1097/ALN.0b013e318238be93.
2
Lipid resuscitation of bupivacaine toxicity: long-chain triglyceride emulsion provides benefits over long- and medium-chain triglyceride emulsion.布比卡因中毒的脂质复苏：长链甘油三酯乳剂优于长链和中链甘油三酯乳剂。
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Triglyceride micro-emulsion for detoxification of acute pharmacotoxicity.用于急性药物中毒解毒的甘油三酯微乳剂。
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本文引用的文献

1
Lipid resuscitation of bupivacaine toxicity: long-chain triglyceride emulsion provides benefits over long- and medium-chain triglyceride emulsion.布比卡因中毒的脂质复苏：长链甘油三酯乳剂优于长链和中链甘油三酯乳剂。
Anesthesiology. 2011 Dec;115(6):1219-28. doi: 10.1097/ALN.0b013e318238be73.
2
Phosphorylation of GSK-3β mediates intralipid-induced cardioprotection against ischemia/reperfusion injury.GSK-3β 的磷酸化介导脂肪乳剂诱导的缺血/再灌注损伤心肌保护作用。
Anesthesiology. 2011 Aug;115(2):242-53. doi: 10.1097/ALN.0b013e318223b8b9.
3
Models and mechanisms of local anesthetic cardiac toxicity: a review.局部麻醉药心脏毒性的模型和机制：综述。
Reg Anesth Pain Med. 2010 Mar-Apr;35(2):167-76. doi: 10.1097/aap.0b013e3181d231b9.
4
Local anesthetic systemic toxicity: a historical perspective.局部麻醉药全身毒性：历史透视。
Reg Anesth Pain Med. 2010 Mar-Apr;35(2):162-6. doi: 10.1097/AAP.0b013e3181d2306c.
5
ASRA practice advisory on local anesthetic systemic toxicity.全身麻醉中毒的 ASRA 实践指南
Reg Anesth Pain Med. 2010 Mar-Apr;35(2):152-61. doi: 10.1097/AAP.0b013e3181d22fcd.
6
Successful resuscitation after ropivacaine and lidocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child.小儿腰丛神经阻滞术后罗哌卡因和利多卡因诱发室性心律失常后的成功复苏。
Anesth Analg. 2008 May;106(5):1572-4, table of contents. doi: 10.1213/01.ane.0000286176.55971.f0.
7
Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest.成功使用20%脂质乳剂对疑似布比卡因相关心脏骤停患者进行复苏。
Anesthesiology. 2006 Jul;105(1):217-8. doi: 10.1097/00000542-200607000-00033.
8
Emergent cardiopulmonary bypass for bupivacaine cardiotoxicity.布比卡因心脏毒性的紧急体外循环
J Cardiothorac Vasc Anesth. 2003 Jun;17(3):357-8. doi: 10.1016/s1053-0770(03)00062-4.
9
Bupivacaine inhibits acylcarnitine exchange in cardiac mitochondria.布比卡因抑制心肌线粒体中的酰基肉碱交换。
Anesthesiology. 2000 Feb;92(2):523-8. doi: 10.1097/00000542-200002000-00036.
10
Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats.脂质输注预处理或复苏可改变大鼠对布比卡因诱导的心搏停止的剂量反应。
Anesthesiology. 1998 Apr;88(4):1071-5. doi: 10.1097/00000542-199804000-00028.

From bedside to bench and back: perfecting lipid emulsion therapy for local anesthetic toxicity.

作者信息

Killoran Peter V, Cattano Davide

出版信息

Anesthesiology. 2011 Dec;115(6):1151-2. doi: 10.1097/ALN.0b013e318238be93.

DOI:10.1097/ALN.0b013e318238be93
PMID:22011714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4867467/
Abstract
摘要