Division of Surgical Oncology, Department of Surgery, Wright State University Boonshoft School of Medicine, One Wyoming Street, WCHE 7000, Dayton, OH 45409, USA.
Surg Endosc. 2012 Feb;26(2):468-72. doi: 10.1007/s00464-011-1902-z. Epub 2011 Oct 20.
Laparoscopic liver resection for malignant disease has shown short-term benefit. This study aimed to compare in-house, 30-day, and 1-year morbidity between laparoscopic and open liver resections.
The charts for all patients who underwent liver resection for malignant disease between April 2006 and October 2009 were reviewed. Patient, operative, and outcomes data at 30 days and 1 year were collected.
For 76 patients, 49 open and 27 laparoscopic resections were performed. The two groups were similar in terms of age, gender, body mass index (BMI), extent of liver resection, use of ablation therapy, and tumor pathology (P > 0.05). The laparoscopic group had less blood loss (P = 0.004) and shorter hospital stays (P = 0.002). During their hospital stay, patients treated laparoscopically had fewer complications, but the difference was not significant. Home disposition was similar in the laparoscopic (96%) and open (90%) groups. More patients were readmitted at 30 days (2 vs. 9; P = 0.31) and 1 year (4 vs. 19; P = 0.04) in the open group. The all-cause 1-year mortality rates were similar between the laparoscopic and open groups (14.8% vs. 10.2%).
The benefits of laparoscopic liver resection may extend beyond the initial postoperative period, with fewer readmissions despite shorter hospital stays. This also may suggest lower long-term hospital costs.
腹腔镜肝切除术治疗恶性疾病已显示出短期获益。本研究旨在比较腹腔镜和开腹肝切除术的院内、30 天和 1 年发病率。
回顾了 2006 年 4 月至 2009 年 10 月期间所有接受恶性疾病肝切除术的患者的病历。收集了 30 天和 1 年时的患者、手术和结局数据。
76 例患者中,49 例行开腹手术,27 例行腹腔镜手术。两组在年龄、性别、体重指数(BMI)、肝切除范围、消融治疗的使用和肿瘤病理方面相似(P>0.05)。腹腔镜组出血量较少(P=0.004),住院时间较短(P=0.002)。住院期间,腹腔镜组并发症较少,但差异无统计学意义。腹腔镜组(96%)和开腹组(90%)的居家处置率相似。30 天(2 例比 9 例;P=0.31)和 1 年(4 例比 19 例;P=0.04)时,开腹组的再入院人数更多。腹腔镜组和开腹组的全因 1 年死亡率相似(14.8%比 10.2%)。
腹腔镜肝切除术的益处可能会超出初始术后时期,尽管住院时间较短,但再入院人数较少。这也可能表明长期住院费用较低。