Department of Hepato-Biliary-Pancreato-Vascular Surgery, the First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Xiamen, 361003, Fujian Province, China.
Surg Endosc. 2012 Mar;26(3):783-9. doi: 10.1007/s00464-011-1952-2. Epub 2011 Oct 20.
Obese patients are generally believed to be at increased risk for surgery compared with those who are not obese. A meta-analysis was performed to assess the outcomes of laparoscopic colorectal surgery in obese and nonobese patients.
A systematic literature search from inception to June 2011 was performed. Pooled odds ratios (OR) and weighted mean differences (WMD) with 95% confidence intervals (95% CI) were calculated using the fixed effects model or random effects model.
Eight observational studies identified and matched the selection criteria. Conversion rates (OR: 2.31, 95% CI: 1.74-3.08), operating time (WMD: 15.33, 95% CI: 1.81-28.85), and postoperative morbidity (OR: 2.11; 95% CI: 1.3-3.42) were all significantly increased in the obese group. Length of hospital stay and mortality were similar in both groups. For patients with cancer, there was no difference between groups for the number of harvested nodes and length of specimen.
Obesity is associated with increased conversion rate, operating time, and postoperative morbidity of laparoscopic colorectal surgery but does not affect surgical safety or oncological security.
肥胖患者相较于非肥胖患者,其手术风险通常被认为更高。本研究通过荟萃分析评估肥胖与非肥胖患者行腹腔镜结直肠手术的结局。
对从建库至 2011 年 6 月期间发表的文献进行系统检索。使用固定效应模型或随机效应模型计算合并比值比(OR)和加权均数差值(WMD)及其 95%置信区间(95%CI)。
8 项观察性研究符合纳入标准并进行了匹配。肥胖组中转行率(OR:2.31,95%CI:1.74-3.08)、手术时间(WMD:15.33,95%CI:1.81-28.85)和术后发病率(OR:2.11;95%CI:1.3-3.42)均显著增加,而住院时间和死亡率在两组间无差异。对于癌症患者,两组间的淋巴结清扫数目和标本长度无差异。
肥胖与腹腔镜结直肠手术中转开腹率、手术时间和术后发病率增加相关,但并不影响手术安全性或肿瘤学安全性。