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两例免疫功能低下儿童感染蒂尔堡分枝杆菌:在培养阴性分枝杆菌病诊断中分子工具的重要性。

"Mycobacterium tilburgii" infection in two immunocompromised children: importance of molecular tools in culture-negative mycobacterial disease diagnosis.

机构信息

Department of Pediatrics, Ped. Infect. Dis. & Immunol., Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 60, 3000 CB Rotterdam, The Netherlands.

出版信息

J Clin Microbiol. 2011 Dec;49(12):4409-11. doi: 10.1128/JCM.05460-11. Epub 2011 Oct 19.

Abstract

"Mycobacterium tilburgii" is a nontuberculous mycobacterium that cannot be cultured by current techniques. It is described as causing disseminated disease in adults. We present the first cases of disseminated disease in 2 immunocompromised children. This paper stresses the importance of molecular techniques for correct mycobacterial identification and guidance to immunological diagnosis.

摘要

“分枝杆菌蒂尔堡”是一种无法通过当前技术培养的非结核分枝杆菌。据描述,它可引起成人播散性疾病。我们报告了首例 2 例免疫功能低下儿童播散性疾病。本文强调了分子技术在正确鉴定分枝杆菌和指导免疫诊断方面的重要性。

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