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早产儿胸腺大小的超声测量:印度次大陆胸腺大小的预测模型。

Sonographic measurement of thymic size in preterm infants: prediction model for thymic size in the Indian subcontinent.

机构信息

Department of Radiodiagnosis, Pandit Bhagwat Dayal Sharma, Post Graduate Institute of Medical Sciences, Rohtak, 124001, Haryana, India.

出版信息

Indian J Pediatr. 2012 Jun;79(6):764-8. doi: 10.1007/s12098-011-0594-7. Epub 2011 Oct 20.

DOI:10.1007/s12098-011-0594-7
PMID:22012145
Abstract

OBJECTIVE

To study the relationship of thymic size in vivo in preterm infants with gestational age (GA), birth-weight (BW) and length of the baby.

METHODS

Two hundred consecutive preterm, appropriate for GA, asymptomatic neonates with GA between 26 and 36 wk and BW between 1000 and 2700 g were examined during the first week following delivery. Neonates of mothers with medical complications were excluded from the study. Thymic size was assessed sonographically and thymic index (Ti) was calculated.

RESULTS

The mean gestational age was 32.62 ± 2.32 wk, the mean birth weight was 1850 ± 41 g and the mean length was 42.93 ± 3.09 cm. The number of boys were 109 (54.5%) and the number of girls were 91 (45.5%). The mean Ti in boys (4.11 ± 2.10) was similar to that in girls (4.36 ± 2.05). Thymic index was positively correlated with GA and length and the correlation was not significant with BW and sex of the infant.

CONCLUSIONS

The sonographic method is a safe and effective technique for measuring the size of the thymus in preterm infants. A normal range of Ti has been established and correlates positively with GA and length and negatively with BW and sex of the preterm infants of the Indian subcontinent.

摘要

目的

研究早产儿体内胸腺大小与胎龄(GA)、出生体重(BW)和婴儿身长的关系。

方法

对 200 例胎龄 26-36 周、BW 为 1000-2700g、无并发症的早产儿进行研究,在出生后第一周内进行超声检查。排除母亲有医学并发症的新生儿。评估胸腺大小并计算胸腺指数(Ti)。

结果

平均胎龄为 32.62±2.32 周,平均出生体重为 1850±41g,平均身长为 42.93±3.09cm。男孩 109 例(54.5%),女孩 91 例(45.5%)。男孩的平均 Ti(4.11±2.10)与女孩相似(4.36±2.05)。Ti 与 GA 和身长呈正相关,与 BW 和婴儿性别无显著相关性。

结论

超声方法是测量早产儿胸腺大小的一种安全有效的方法。已经建立了正常的 Ti 范围,与 GA 和身长呈正相关,与 BW 和婴儿性别呈负相关。

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本文引用的文献

1
Analysis of the thymus in 151 healthy infants from 0 to 2 years of age.对151名0至2岁健康婴儿的胸腺进行分析。
J Ultrasound Med. 2004 Oct;23(10):1321-6. doi: 10.7863/jum.2004.23.10.1321.
2
Thymic size in preterm neonates: a sonographic study.早产儿胸腺大小:一项超声研究。
Acta Paediatr. 2003 Jul;92(7):817-22.
3
Thymus size and its relationship to perinatal events.胸腺大小及其与围产期事件的关系。
Acta Paediatr. 2000 Aug;89(8):975-8. doi: 10.1080/080352500750043468.
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Thymus size in preterm infants evaluated by ultrasound. A preliminary report.超声评估早产儿胸腺大小:初步报告
Acta Radiol. 1999 Jan;40(1):37-40. doi: 10.1080/02841859909174400.
5
Sonographic measurement of thymic size in healthy neonates. Relation to clinical variables.健康新生儿胸腺大小的超声测量。与临床变量的关系。
Acta Radiol. 1997 Jan;38(1):95-8. doi: 10.1080/02841859709171249.
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Sonographic measurement of the thymus in infants.婴儿胸腺的超声测量
Eur Radiol. 1996;6(5):700-3. doi: 10.1007/BF00187675.
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Intrauterine growth in length and head circumference as estimated from live births at gestational ages from 26 to 42 weeks.根据孕龄26至42周活产儿估算的宫内身长和头围生长情况。
Pediatrics. 1966 Mar;37(3):403-8.
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New Ballard Score, expanded to include extremely premature infants.新巴拉德评分,扩展至包括极早产儿。
J Pediatr. 1991 Sep;119(3):417-23. doi: 10.1016/s0022-3476(05)82056-6.