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超声心动图在出生时对胸腺的评估：一项初步的队列研究。

Thymus assessments at birth in echocardiography: a preliminary cohort study.

机构信息

Neonatal Unit, Department of Obstetrics and Pathology Pregnancy, Medical University of Lublin, ul. Staszica 16, Lublin, 20-828, Poland.

Chair and Department of Paediatric Nursing, Faculty of Health Sciences, Medical University of Lublin, Lublin, Poland.

出版信息

BMC Pediatr. 2024 Aug 2;24(1):495. doi: 10.1186/s12887-024-04972-z.

DOI:10.1186/s12887-024-04972-z
PMID:39095774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11295333/
Abstract

BACKGROUND

Echocardiography is a tool used in neonatal period to screen for congenital heart defects and to assess the function of the cardiovascular system. It enables obtaining a three-vessel view (3VV) to show how the superior vena cava, the aorta and the pulmonary trunk relate to each other. A 3VV also provides a view of the thymus gland.

METHODS

It is a preliminary study. Using the thymus measurements obtained in echocardiography of neonates delivered in one healthcare centre, a total of 1,331 thymus records were collected and statistically analysed. The study was conducted on group of 321 preterm neonates and 1,010 full-term neonates. The superior mediastinal view (three-vessel view, 3VV) was chosen for thymus measurements, with the parallel vascular system, including the superior vena cava, the aorta and the pulmonary trunk, with visible branching to the right and left pulmonary artery. Thymus width, depth and thymic 3VV index were measured. Thymic 3VV index (TI 3VV) is defined as a product of multipling the width and the depth of the thymus in three-vessel view projection.

RESULTS

Based on a statistical analysis, a correlation was found of 3VV thymus dimensions and thymic 3VV index with body weight, gestational age and body surface area (BSA). These measurements led to the important finding that the TI 3VV value depends on thymus width and depth, more prominently the latter. The 3VV measurement of thymus depth alone can serve as a screening tool to assess the size of the gland.

CONCLUSIONS

Inclusion of thymic measurements in neonatal echocardiography protocol can be used as a screening tool to assess the size of thymus gland.

摘要

背景

超声心动图是新生儿期筛查先天性心脏病和评估心血管系统功能的工具。它可以获得三血管切面（3VV），以显示上腔静脉、主动脉和肺动脉干之间的相互关系。3VV 还提供了胸腺的图像。

方法

这是一项初步研究。通过对一家医疗中心出生的新生儿进行超声心动图检查，获得了胸腺测量值，共收集了 1331 份胸腺记录并进行了统计学分析。研究对象为 321 例早产儿和 1010 例足月儿。选择上纵隔切面（三血管切面，3VV）进行胸腺测量，平行的血管系统包括上腔静脉、主动脉和肺动脉干，可见分支到左右肺动脉。测量胸腺的宽度、深度和胸腺 3VV 指数。胸腺 3VV 指数（TI 3VV）定义为三血管切面投影中胸腺宽度和深度的乘积。

结果

基于统计学分析，发现 3VV 胸腺尺寸和胸腺 3VV 指数与体重、胎龄和体表面积（BSA）之间存在相关性。这些测量结果重要的发现是 TI 3VV 值取决于胸腺的宽度和深度，后者更为显著。单独测量胸腺的 3VV 深度可以作为评估腺体大小的筛查工具。

结论

在新生儿超声心动图检查中纳入胸腺测量可以作为评估胸腺大小的筛查工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c899/11295333/263786355df1/12887_2024_4972_Fig14_HTML.jpg
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BMC Pediatr. 2021 Jan 4;21(1):1. doi: 10.1186/s12887-020-02457-3.
2
Comprehensive state-of-the-art overview of neonatologist performed echocardiography: Steps towards standardization of the use of echocardiography in neonatal intensive care.新生儿科医生进行超声心动图检查的全面前沿综述：新生儿重症监护中超声心动图使用标准化的步骤
Pediatr Res. 2018 Oct;84(4):472-473. doi: 10.1038/s41390-018-0118-5. Epub 2018 Jul 18.
3
Simplifying ultrasound assessment of the fetal heart: Incorporating the complete Three Vessel View into routine screening.
简化胎儿心脏超声评估：将完整的三血管切面纳入常规筛查。
Australas J Ultrasound Med. 2013 Nov;16(4):168-175. doi: 10.1002/j.2205-0140.2013.tb00243.x. Epub 2015 Dec 31.
4
Assessment of thymus size in healthy term neonates using sonography - A study from tertiary care hospital of Central India.使用超声检查评估健康足月儿的胸腺大小——来自印度中部三级护理医院的一项研究。
J Neonatal Perinatal Med. 2015;8(2):143-7. doi: 10.3233/NPM-15814067.
5
Vaccination in patients with primary immune deficiency, secondary immune deficiency and autoimmunity with immune regulatory abnormalities.原发性免疫缺陷、继发性免疫缺陷以及伴有免疫调节异常的自身免疫患者的疫苗接种。
Immunotherapy. 2015;7(12):1273-92. doi: 10.2217/IMT.15.74. Epub 2015 Aug 20.
6
Vaccine use in primary immunodeficiency disorders.原发性免疫缺陷病中的疫苗使用
Vaccine. 2014 Jun 24;32(30):3725-31. doi: 10.1016/j.vaccine.2014.05.022. Epub 2014 May 14.
7
Immunodeficiency in DiGeorge Syndrome and Options for Treating Cases with Complete Athymia.DiGeorge综合征中的免疫缺陷及完全无胸腺病例的治疗选择
Front Immunol. 2013 Oct 31;4:322. doi: 10.3389/fimmu.2013.00322.
8
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BMC Pediatr. 2013 Apr 20;13:59. doi: 10.1186/1471-2431-13-59.
9
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10
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Development. 2011 Sep;138(18):3865-78. doi: 10.1242/dev.059998.