Lee Hae-June, Jin Yeung Bae, Kim Tae-Hong, Pack Jeong-Ki, Kim Nam, Choi Hyung-Do, Lee Jae-Seon, Lee Yun-Sil
Division of Radiation Effects, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
Bioelectromagnetics. 2012 May;33(4):356-64. doi: 10.1002/bem.20715. Epub 2011 Oct 19.
Wireless mobile phones and other telecommunication devices are used extensively in daily life. We therefore examined the effects of combined exposure to radiofrequency electromagnetic fields (RF-EMF) on rat testicular function, specifically with respect to sensitive processes such as spermatogenesis. Male rats were exposed to single code division multiple access (CDMA) and wideband code division multiple access (WCDMA) RF signals for 12 weeks. The RF exposure schedule comprised 45 min/day, 5 days/week for a total of 12 weeks. The whole-body average specific absorption rate (SAR) of CDMA and WCDMA was 2.0 W/kg each or 4.0 W/kg in total. We then investigated the correlates of testicular function such as sperm count in the cauda epididymis, testosterone concentration in the blood serum, malondialdehyde concentrations in the testes and epididymis, frequency of spermatogenesis stages, and appearance of apoptotic cells in the testes. We also immunoblotted for p53, bcl2, GADD45, cyclin G, and HSP70 in the testes of sham- and combined RF-exposed animals. Based on the results, we concluded that simultaneous exposure to CDMA and WCDMA RF-EMFs at 4.0 W/kg SAR did not have any observable adverse effects on rat spermatogenesis.
无线移动电话和其他电信设备在日常生活中被广泛使用。因此，我们研究了射频电磁场（RF-EMF）联合暴露对大鼠睾丸功能的影响，特别是对精子发生等敏感过程的影响。将雄性大鼠暴露于单码分多址（CDMA）和宽带码分多址（WCDMA）射频信号下12周。射频暴露方案为每天45分钟，每周5天，共12周。CDMA和WCDMA的全身平均比吸收率（SAR）均为2.0W/kg，或总计4.0W/kg。然后，我们研究了睾丸功能的相关指标，如附睾尾部的精子计数、血清睾酮浓度、睾丸和附睾中的丙二醛浓度、精子发生阶段的频率以及睾丸中凋亡细胞的出现情况。我们还对假暴露和联合射频暴露动物的睾丸中的p53、bcl2、GADD45、细胞周期蛋白G和HSP70进行了免疫印迹分析。根据结果，我们得出结论，在4.0W/kg SAR下同时暴露于CDMA和WCDMA射频电磁场对大鼠精子发生没有任何可观察到的不利影响。
