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CDMA 和 WCDMA 电磁场同时联合暴露对大鼠血清激素水平的影响。

Effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on serum hormone levels in rats.

机构信息

Division of Radiation Effects, Korea Institute of Radiological and Medical Sciences, Seoul 139-706, Korea.

出版信息

J Radiat Res. 2013 May;54(3):430-7. doi: 10.1093/jrr/rrs120. Epub 2012 Dec 13.

Abstract

Despite more than a decade of research on the endocrine system, there have been no published studies about the effects of concurrent exposure of radiofrequency electromagnetic fields (RF-EMF) on this system. The present study investigated the several parameters of the endocrine system including melatonin, thyroid stimulating hormone, stress hormone and sex hormone after code division multiple access (CDMA, 849 MHz) and wideband code division multiple access (WCDMA, 1.95 GHz) signals for simultaneous exposure in rats. Sprague-Dawley rats were exposed to RF-EMF signals for 45 min/day, 5 days/week for up to 8 weeks. The whole-body average specific absorption rate (SAR) of CDMA or WCDMA was 2.0 W/kg (total 4.0 W/kg). At 4 and 8 weeks after the experiment began, each experimental group's 40 rats (male 20, female 20) were autopsied. Exposure for 8 weeks to simultaneous CDMA and WCDMA RF did not affect serum levels in rats of melatonin, thyroid stimulating hormone (TSH), triiodothyronine (T3) and thyroxin (T4), adrenocorticotropic hormone (ACTH) and sex hormones (testosterone and estrogen) as assessed by the ELISA method.

摘要

尽管对内分泌系统的研究已经超过了十年,但目前还没有关于同时暴露于射频电磁场 (RF-EMF) 对该系统影响的研究。本研究调查了内分泌系统的几个参数,包括褪黑素、促甲状腺激素、应激激素和性激素,这些参数在大鼠同时暴露于码分多址 (CDMA,849 MHz) 和宽带码分多址 (WCDMA,1.95 GHz) 信号后发生了变化。Sprague-Dawley 大鼠每天接受 RF-EMF 信号照射 45 分钟,每周 5 天,持续 8 周。CDMA 或 WCDMA 的全身平均比吸收率 (SAR) 为 2.0 W/kg(总 4.0 W/kg)。在实验开始后 4 周和 8 周,每个实验组的 40 只大鼠(雄性 20 只,雌性 20 只)进行尸检。通过 ELISA 方法评估,8 周同时暴露于 CDMA 和 WCDMA RF 对大鼠血清中褪黑素、促甲状腺激素 (TSH)、三碘甲状腺原氨酸 (T3) 和甲状腺素 (T4)、促肾上腺皮质激素 (ACTH) 和性激素(睾酮和雌激素)水平没有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a5/3650745/02062a9bbaf5/rrs12001.jpg

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