无刹车驾驶：Kv7 钾通道的分子病理生理学。
Driving with no brakes: molecular pathophysiology of Kv7 potassium channels.
机构信息
Department of Health Science, University of Molise, Campobasso, Italy.
出版信息
Physiology (Bethesda). 2011 Oct;26(5):365-76. doi: 10.1152/physiol.00009.2011.
PMID:22013194
Abstract
Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.
摘要
Kv7 钾通道调节神经元、感觉和肌肉细胞的兴奋性。本文描述了 Kv7 钾通道的分子结构、生理作用以及在遗传性通道病中的作用，强调了它们作为治疗多种人类疾病的药理学靶点的重要性。
Zotero 插件