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使用传统喉罩气道在日间手术麻醉中异氟烷和七氟烷的比较

Comparison of isoflurane and sevoflurane in anaesthesia for day care surgeries using classical laryngeal mask airway.

作者信息

Sahu Dinesh Kumar, Kaul Vinca, Parampill Reena

机构信息

Department of Anaesthesiology and Advanced Pain Management, Jagjivanram Railway Hospital, Mumbai, India.

出版信息

Indian J Anaesth. 2011 Jul;55(4):364-9. doi: 10.4103/0019-5049.84857.

DOI:10.4103/0019-5049.84857
PMID:22013252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3190510/
Abstract

BACKGROUND

In the present study, we compared isoflurane with sevoflurane in day care surgeries in order to determine the suitability of each agent for anaesthesia with Classical laryngeal mask airway (LMA).

AIMS

The aim of this study has been to compare isoflurane and sevoflurane as maintenance anaesthetic agents in day care surgeries with respect to intraoperative haemodynamics, recovery profile, time of first postoperative analgesia and pain score, adverse effects when used with classical LMA.

SETTINGS AND DESIGN

This open - level, prospective randomized study was carried out on 60 patients who were admitted on a day care basis for elective short surgical procedures.

METHODS

The patients were randomly assigned to one of the two study groups of 30 patients each. First group was maintained on isoflurane and second on sevoflurane as inhalational agent.

STATISTICAL ANALYSIS

The observations obtained in both the groups were recorded and tabulated. Statistical analysis was carried out using the Student t test, Chi-square test, Mann-Whitney test.

RESULTS

Emergence from Sevoflurane was significantly quicker as compared to isoflurane. Sevoflurane group also showed earlier discharge time from the post anaesthesia care unit (PACU)-1 as compared to isoflurane group, but discharge time was same from the PACU-1. Isoflurane has more incidences of mild airway hyper reactivity when compared to sevoflurane.

CONCLUSIONS

It can be concluded that both isoflurane and sevoflurane are suitable for day care anaesthesia. Sevoflurane has little advantages of less airway hyper reactivity and quicker emergence and discharge from PACU-1.

摘要

背景

在本研究中,我们在日间手术中比较了异氟烷和七氟烷,以确定每种药物与经典喉罩气道(LMA)用于麻醉的适用性。

目的

本研究的目的是比较异氟烷和七氟烷作为日间手术中维持麻醉药物时在术中血流动力学、恢复情况、首次术后镇痛时间和疼痛评分、与经典LMA联合使用时的不良反应方面的差异。

设置与设计

本开放性、前瞻性随机研究对60例择期接受短期手术的日间入院患者进行。

方法

患者被随机分为两个研究组,每组30例。第一组以异氟烷作为吸入麻醉药维持麻醉,第二组以七氟烷作为吸入麻醉药维持麻醉。

统计分析

记录并整理两组观察到的数据。使用学生t检验、卡方检验、曼-惠特尼检验进行统计分析。

结果

与异氟烷相比,七氟烷的苏醒明显更快。与异氟烷组相比,七氟烷组从麻醉后恢复室(PACU)-1出院的时间也更早,但从PACU-1出院的时间相同。与七氟烷相比,异氟烷引起轻度气道高反应性的发生率更高。

结论

可以得出结论,异氟烷和七氟烷都适用于日间麻醉。七氟烷在气道高反应性较低、苏醒更快以及从PACU-1出院更早方面具有一些优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ede/3190510/b1d5310fda74/IJA-55-364-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ede/3190510/4901f6271816/IJA-55-364-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ede/3190510/b1d5310fda74/IJA-55-364-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ede/3190510/4901f6271816/IJA-55-364-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ede/3190510/b1d5310fda74/IJA-55-364-g004.jpg

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