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1
Preventing ventilator-associated pneumonia in the United States: a multicenter mixed-methods study.美国预防呼吸机相关性肺炎:一项多中心混合方法研究。
Infect Control Hosp Epidemiol. 2008 Oct;29(10):933-40. doi: 10.1086/591455.
2
Continuous aspiration of subglottic secretions in the prevention of ventilator-associated pneumonia in the postoperative period of major heart surgery.在心脏大手术后的术后阶段,持续吸引声门下分泌物以预防呼吸机相关性肺炎。
Chest. 2008 Nov;134(5):938-946. doi: 10.1378/chest.08-0103. Epub 2008 Jul 18.
3
Closed tracheal suction systems for prevention of ventilator-associated pneumonia.用于预防呼吸机相关性肺炎的封闭式气管吸引系统
Br J Anaesth. 2008 Mar;100(3):299-306. doi: 10.1093/bja/aem403. Epub 2008 Feb 4.
4
Closed tracheal suction systems versus open tracheal suction systems for mechanically ventilated adult patients.用于机械通气成年患者的密闭式气管吸痰系统与开放式气管吸痰系统的比较
Cochrane Database Syst Rev. 2007 Oct 17;2007(4):CD004581. doi: 10.1002/14651858.CD004581.pub2.
5
Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta-analysis.机械通气重症监护患者的开放式与封闭式气管内吸痰系统:一项荟萃分析
Crit Care Med. 2007 Jan;35(1):260-70. doi: 10.1097/01.CCM.0000251126.45980.E8.
6
Impact of the suctioning system (open vs. closed) on the incidence of ventilation-associated pneumonia: Meta-analysis of randomized controlled trials.吸痰系统(开放式与封闭式)对呼吸机相关性肺炎发病率的影响:随机对照试验的荟萃分析
Intensive Care Med. 2006 Sep;32(9):1329-35. doi: 10.1007/s00134-006-0241-3. Epub 2006 Jun 21.
7
The 100,000 lives campaign: setting a goal and a deadline for improving health care quality.“拯救十万生命”运动:设定改善医疗质量的目标和期限。
JAMA. 2006 Jan 18;295(3):324-7. doi: 10.1001/jama.295.3.324.
8
Open and closed-circuit endotracheal suctioning in acute lung injury: efficiency and effects on gas exchange.急性肺损伤中开放式与封闭式气管内吸痰:效率及对气体交换的影响
Anesthesiology. 2006 Jan;104(1):39-47. doi: 10.1097/00000542-200601000-00008.
9
Clinical and economic consequences of ventilator-associated pneumonia: a systematic review.呼吸机相关性肺炎的临床和经济后果:一项系统综述
Crit Care Med. 2005 Oct;33(10):2184-93. doi: 10.1097/01.ccm.0000181731.53912.d9.
10
Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia.成人医院获得性肺炎、呼吸机相关性肺炎和医疗保健相关性肺炎管理指南。
Am J Respir Crit Care Med. 2005 Feb 15;171(4):388-416. doi: 10.1164/rccm.200405-644ST.

比较使用/不使用密闭式吸痰系统的间歇性声门下分泌物引流对呼吸机相关性肺炎发生率的影响。

Comparing influence of intermittent subglottic secretions drainage with/without closed suction systems on the incidence of ventilator associated pneumonia.

作者信息

Juneja Deven, Javeri Yash, Singh Omender, Nasa Prashant, Pandey Rameshwar, Uniyal Bhupesh

机构信息

Department of Critical Care Medicine, Max Super Speciality Hospital, New Delhi, India.

出版信息

Indian J Crit Care Med. 2011 Jul;15(3):168-72. doi: 10.4103/0972-5229.84902.

DOI:10.4103/0972-5229.84902
PMID:22013309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3190468/
Abstract

CONTEXT

Intermittent subglottic drainage (ISD) of secretions is recommended for prevention of ventilator-associated pneumonia (VAP) as it reduces microaspiration from the area around the cuff. Poor suction techniques can contribute to VAP, hence closed suction system (CSS) may have theoretical benefit in VAP prevention. Combination of these two techniques may provide added advantage.

AIMS

To study the influence of ISD with/without CSS on the incidence of VAP.

MATERIALS AND METHODS

Data from 311 patients requiring mechanical ventilation (MV) for more than 72 hours were collected retrospectively. They were divided into four groups as follows: group A, no intervention; group B, only CSS; group C, only ISD; and group D, ISD with CSS. These groups were compared with respect to incidence of VAP, duration of MV, length of ICU and hospital stay and ICU mortality.

RESULTS

Patients in the four groups were comparable with respect to age, sex ratio and admission Acute Physiology and Chronic Health Evaluation (APACHE) II scores. Incidence of VAP per 1000 ventilator days in groups A, B, C, and D were 25, 23.9, 15.7 and 14.3, respectively (P=0.04). There was no significant difference in the duration of MV (P=0.33), length of ICU (P=0.55) and hospital stay (P=0.36) and ICU mortality (P=0.9) among the four groups.

CONCLUSIONS

ISD of secretions reduces the incidence of VAP. CSS alone or in combination with ISD has no significant effect on VAP incidence. Hence, ISD may be recommended for VAP prevention, but indications other than VAP prevention should determine the type of the suction system.

摘要

背景

推荐对分泌物进行间歇性声门下引流(ISD)以预防呼吸机相关性肺炎(VAP),因为它可减少套囊周围区域的微量误吸。较差的吸痰技术可能导致VAP,因此封闭式吸痰系统(CSS)在预防VAP方面可能具有理论上的益处。这两种技术的联合应用可能会带来额外的优势。

目的

研究有无CSS的ISD对VAP发生率的影响。

材料与方法

回顾性收集311例需要机械通气(MV)超过72小时的患者的数据。他们被分为四组如下:A组,不进行干预;B组,仅使用CSS;C组,仅使用ISD;D组,ISD联合CSS。比较这些组在VAP发生率、MV持续时间、ICU和住院时间以及ICU死亡率方面的情况。

结果

四组患者在年龄、性别比和入院急性生理与慢性健康状况评估(APACHE)II评分方面具有可比性。A、B、C、D组每1000个呼吸机日的VAP发生率分别为25、23.9、15.7和14.3(P = 0.04)。四组之间在MV持续时间(P = 0.33)、ICU住院时间(P = 0.55)、住院时间(P = 0.36)和ICU死亡率(P = 0.9)方面无显著差异。

结论

分泌物的ISD可降低VAP的发生率。单独使用CSS或与ISD联合使用对VAP发生率无显著影响。因此,对于VAP预防可推荐使用ISD,但除VAP预防之外的其他指征应决定吸痰系统的类型。