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本文引用的文献

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Medicine as a corporate enterprise, patient welfare centered profession, or patient welfare centered professional enterprise?医学是一个企业化的行业、以患者福祉为中心的职业,还是以患者福祉为中心的专业企业?
Mens Sana Monogr. 2005 Nov;3(2):19-51. doi: 10.4103/0973-1229.27881.
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Clinical practice guidelines and industry.临床实践指南与行业
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The image of pharma.制药行业的形象。
Mens Sana Monogr. 2007 Jan;5(1):37-44. doi: 10.4103/0973-1229.32148.
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Academia, journal publishing and the bio-medical industry.学术界、期刊出版与生物医学产业。
Mens Sana Monogr. 2007 Jan;5(1):11-4. doi: 10.4103/0973-1229.32144.
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The role of litigation in defining drug risks.诉讼在界定药物风险方面的作用。
JAMA. 2007 Jan 17;297(3):308-11. doi: 10.1001/jama.297.3.308.
6
Lapses at the new England journal of medicine.《新英格兰医学杂志》的失误。
J R Soc Med. 2006 Aug;99(8):380-2. doi: 10.1177/014107680609900802.
7
Commercial influence and the content of medical journals.商业影响与医学期刊内容
BMJ. 2006 Jun 17;332(7555):1444-7. doi: 10.1136/bmj.332.7555.1444.
8
Pharmaceutical company gifts: from voluntary standards to legal demands.
Hastings Cent Rep. 2006 May-Jun;36(3):8-9. doi: 10.1353/hcr.2006.0039.
9
On the origin of great ideas: science in the age of big pharma.论伟大思想的起源:大制药时代的科学
Hastings Cent Rep. 2005 Nov-Dec;35(6):17-9.
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A different medicine is possible.另一种医学是有可能的。
Psychother Psychosom. 2006;75(1):1-3. doi: 10.1159/000089219.

生物医学研究与企业利益:学术自由问题

Biomedical research and corporate interests: a question of academic freedom.

作者信息

McHenry Leemon

机构信息

Lecturer in Philosophy, California State University, Northridge, USA.

出版信息

Mens Sana Monogr. 2008 Jan;6(1):146-56. doi: 10.4103/0973-1229.37086.

DOI:10.4103/0973-1229.37086
PMID:22013356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3190547/
Abstract

The current situation in medicine has been described as a crisis of credibility, as the profit motive of industry has taken control of clinical trials and the dissemination of data. Pharmaceutical companies maintain a stranglehold over the content of medical journals in three ways: (1) by ghostwriting articles that bias the results of clinical trials, (2) by the sheer economic power they exert on journals due to the purchase of drug advertisements and journal reprints, and (3) by the threat of legal action against those researchers who seek to correct the misrepresentation of study results. This paper argues that Karl Popper's critical rationalism provides a corrective to the failure of academic freedom in biomedical research.

摘要

医学领域的当前状况被描述为一场信任危机,因为行业的逐利动机已经掌控了临床试验和数据传播。制药公司通过三种方式对医学期刊的内容保持着严格控制:(1)通过代笔撰写文章来歪曲临床试验结果;(2)凭借购买药品广告和期刊重印本对期刊施加的巨大经济影响力;(3)对那些试图纠正研究结果不实陈述的研究人员采取法律行动的威胁。本文认为,卡尔·波普尔的批判理性主义为生物医学研究中学术自由的失败提供了一种纠正。