Hu Yi-yang, Peng Jing-hua, Feng Qin
Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Sep;31(9):1269-72.
In recent years, the pathogenesis of "gut-liver axis" in alcoholic and nonalcoholic fatty liver disease has attracted more attention in this field. In this paper, the relationship among fatty liver, gut-permeability, gut-derived endotoxin, and gut microbiota was systematically clarified. Based on the researches of treatment and prevention of fatty liver and gut injury by Chinese medicine, the gut is believed as the curative target for fatty liver disease, which not only is the modern annotation for the Chinese medicine practice, but also might possibly become an important view angle and strategy for fatty liver disease treatment.
近年来，酒精性和非酒精性脂肪性肝病中“肠-肝轴”的发病机制在该领域受到了更多关注。本文系统阐明了脂肪肝、肠道通透性、肠道源性内毒素和肠道微生物群之间的关系。基于中医药对脂肪肝和肠道损伤的防治研究，肠道被认为是脂肪性肝病的治疗靶点，这既是中医实践的现代诠释，也可能成为脂肪性肝病治疗的重要视角和策略。
