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对血吸虫功能生物学的深入了解。

Insights into the functional biology of schistosomes.

机构信息

School of Life Sciences, Kingston University, Kingston upon Thames, Surrey KT12EE, UK.

出版信息

Parasit Vectors. 2011 Oct 20;4:203. doi: 10.1186/1756-3305-4-203.

Abstract

The need to discover new treatments for human schistosomiasis has been an important driver for molecular research on schistosomes, a major breakthrough being the publication of the Schistosoma mansoni and Schistosoma japonicum genomes in 2009. This 'Primer' considers recent advances in the understanding of schistosome biology by providing a snapshot of selected areas of contemporary functional schistosome research, including that on the genome, the tegument, cell signalling and developmental biology, offering biologists a valuable insight into the life of these fascinating parasites at the basic and molecular level.

摘要

发现治疗人类血吸虫病的新方法一直是血吸虫分子研究的重要动力,其中一个重大突破是 2009 年公布了曼氏血吸虫和日本血吸虫的基因组。本《概论》通过提供当代功能血吸虫研究选定领域的快照,考虑了对血吸虫生物学理解的最新进展,包括基因组、表皮、细胞信号和发育生物学,为生物学家提供了一个有价值的视角,了解这些迷人寄生虫在基础和分子水平上的生活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f45/3206467/b9e7a994ce77/1756-3305-4-203-1.jpg

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