Istituto Superiore di Sanità, Rome, Italy.
Epidemiol Infect. 2012 Jul;140(7):1193-206. doi: 10.1017/S0950268811002020. Epub 2011 Oct 21.
A retrospective telephone survey (n = 3490) was conducted in Italy between 2008 and 2009 to estimate the occurrence of self-reported acute gastrointestinal illness (AGI) and to describe subjects' recourse to healthcare, using a symptom-based case definition. Three hundred and ten AGI cases were identified. The annual incidence rate was 1.08 episodes/person-year (95% confidence interval 0.90-1.14). The proportion of subjects consulting physicians was 39.5% while only 0.3% submitted a specimen for laboratory investigation. Risk factors for AGI and medical care-seeking were identified using logistic regression analysis. Females, children and young adults had a significantly higher incidence rate of AGI. Factors associated with medical care-seeking were age <10 years, presence of fever, diarrhoea, and duration of illness >3 days. Our results provide a relevant contribution towards estimating the global burden of AGI using standard methods that ensure a good level of comparability with other studies.
2008 年至 2009 年期间,意大利进行了一项回顾性电话调查(n=3490),以估计自述急性胃肠道疾病(AGI)的发生情况,并使用基于症状的病例定义描述患者寻求医疗保健的情况。确定了 310 例 AGI 病例。年发病率为 1.08 例/人年(95%置信区间 0.90-1.14)。咨询医生的患者比例为 39.5%,而只有 0.3%的患者提交样本进行实验室检查。使用逻辑回归分析确定了 AGI 和寻求医疗保健的危险因素。女性、儿童和青年的 AGI 发病率明显更高。与医疗保健寻求相关的因素包括年龄<10 岁、发热、腹泻和疾病持续时间>3 天。我们的研究结果为使用确保与其他研究具有良好可比性的标准方法估算 AGI 的全球负担提供了重要贡献。