School of Health Management, Harbin Medical University, Harbin, China.
Heilongjiang Provincial Center for Disease, Control and Prevention, Harbin, China.
Front Public Health. 2022 Jun 3;10:905458. doi: 10.3389/fpubh.2022.905458. eCollection 2022.
Acute gastroenteritis is an important and highly prevalent public health problem worldwide. The purpose of this study was to assess the economic burden of disease and its influencing factors in patients with acute gastroenteritis in Heilongjiang Province, China.
A multi-stage stratified random sampling method was used in a face-to-face household survey in 2018. Demographic and socioeconomic characteristics, clinical symptoms, suspicious dietary history, and disease treatment information were collected from 19,647 respondents. One-way analysis of variance and multiple stepwise regression analysis were used to investigate the factors associated with the economic burden of acute gastroenteritis. Quantitative risk analysis and sensitivity analysis were performed to estimate the uncertainty and risk factors of the economic burden of acute gastroenteritis.
The total economic burden of patients with acute gastroenteritis was 63,969.22 CNY (Chinese Yuan), of which the direct economic burden accounted for 63.82%; the per capita economic burden was 131.35 CNY per month. Age, region, disease duration, and disease treatment were the main factors significantly associated with the economic burden of acute gastroenteritis ( < 0.05). The average economic burden of patients with acute gastroenteritis was approximately 571.84 CNY/person (95% CI: 227-1,459). Sensitivity analysis showed that the greatest impact was from the indirect economic burden.
Acute gastroenteritis brings a substantial health burden to patients due to its high incidence. The economic burden of self-purchased drugs and the indirect economic burden of patients cannot be ignored. To better estimate the economic burden of acute gastroenteritis in China, further studies on the pathogen-specific economic burden of acute gastroenteritis are required.
急性肠胃炎是全球范围内一个重要且高发的公共卫生问题。本研究旨在评估中国黑龙江省急性肠胃炎患者的疾病经济负担及其影响因素。
2018 年采用多阶段分层随机抽样方法，对 19647 名受访者进行面对面入户调查，收集人口统计学和社会经济学特征、临床症状、可疑饮食史和疾病治疗信息。采用单因素方差分析和多元逐步回归分析调查与急性肠胃炎经济负担相关的因素。采用定量风险分析和敏感性分析估计急性肠胃炎经济负担的不确定性和风险因素。
急性肠胃炎患者的总经济负担为 63969.22 元人民币（CNY），其中直接经济负担占 63.82%；人均经济负担为每月 131.35 元人民币。年龄、地区、疾病持续时间和疾病治疗是与急性肠胃炎经济负担显著相关的主要因素（<0.05）。急性肠胃炎患者的平均经济负担约为 571.84 元人民币/人（95%CI：227-1459）。敏感性分析表明，间接经济负担的影响最大。
由于急性肠胃炎发病率高，给患者带来了沉重的健康负担。自购药物的经济负担和患者的间接经济负担不容忽视。为了更好地估计中国急性肠胃炎的经济负担，需要进一步研究急性肠胃炎病原体特异性的经济负担。
