Pehnec Gordana, Jazbec Anamarija, Vađić Vladimira, Pavlović Mladen
Institute for Medical Research and Occupational Health, Ksaverska c. 2, Zagreb, Croatia.
Arch Environ Occup Health. 2011;66(4):223-30. doi: 10.1080/19338244.2011.564229.
The study examines the influence of naturally elevated ozone concentrations and some meteorological variables on the lung function of untrained volunteers walking in an unpolluted mountain area. Forty male participants between 18 and 70 years (smokers and nonsmokers) walked at the top of Medvednica Mountain near Zagreb, Croatia, at approximately 1000 m above sea level (a.s.l.) and engaged in other recreational activities for at least 1 hour. Forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV(1)) of the participants were measured at arrival and before they left the mountain. Regression analysis showed a statistically significant influence of environmental variables on lung function tests. However, all variables together explained less than 35% variability of FVC and 41% variability of FEV(1). The results suggest that short-term exposure to ozone may affect lung function tests, but no more than temperature and humidity. FEV(1) was found to be more sensitive to ozone than FVC. Smoking habit also had an important role in subject's sensitivity to ozone.
该研究考察了自然升高的臭氧浓度及一些气象变量对在未受污染山区行走的未经训练志愿者肺功能的影响。40名年龄在18至70岁之间的男性参与者(包括吸烟者和非吸烟者)在克罗地亚萨格勒布附近海拔约1000米的梅德韦尼采山顶行走,并进行至少1小时的其他休闲活动。在参与者到达山顶时和离开山顶前测量其用力肺活量(FVC)和一秒用力呼气量(FEV₁)。回归分析表明环境变量对肺功能测试有统计学上的显著影响。然而,所有变量共同解释的FVC变异性不到35%,FEV₁变异性不到41%。结果表明,短期暴露于臭氧可能会影响肺功能测试,但影响程度不超过温度和湿度。研究发现FEV₁对臭氧比FVC更敏感。吸烟习惯在受试者对臭氧的敏感性方面也起着重要作用。