Kansas City University of Medicine and Biosciences, 1750 Independence Ave, Kansas City, MO 64106, USA.
Clin Dermatol. 2011 Nov-Dec;29(6):602-13. doi: 10.1016/j.clindermatol.2011.08.009.
Patients with autoimmune and inflammatory conditions often receive long-term immunosuppressive therapy. Some of the largest patient populations with iatrogenic immunosuppression include patients who have received solid-organ transplants or who have rheumatoid arthritis or psoriasis. Although treatments improve patient outcomes, individuals with immunosuppression subsequently may have an increased risk of skin cancer, including squamous cell carcinoma, basal cell carcinoma, and malignant melanoma.
自身免疫和炎症性疾病患者常需接受长期免疫抑制治疗。因医源性免疫抑制而接受治疗的患者中，人数最多的包括接受实体器官移植的患者、类风湿关节炎或银屑病患者。虽然治疗改善了患者的预后，但接受免疫抑制治疗的个体随后可能会有更高的皮肤癌风险，包括鳞状细胞癌、基底细胞癌和恶性黑色素瘤。
