Department of Dermatology, Massachusetts General Hospital, 50 Staniford St, Ste 200, Boston, MA 02114, USA.
Clin Dermatol. 2011 Nov-Dec;29(6):622-32. doi: 10.1016/j.clindermatol.2011.08.006.
Iatrogenic skin injuries in hospitalized patients range from drug-related complications to those related to procedures. Common drug complications include drug reaction with eosinophilia and systemic symptoms (DRESS), linear immunoglobulin (Ig) A bullous dermatosis, Stevens-Johnson syndrome/toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. Contact dermatitis can result from surgical preparations of chlorhexidine and povidone-iodine, medical adhesives, topical postsurgical ointments, most commonly neomycin and bacitracin, and internal prostheses, including coronary stents, pacemakers, and metal joints. Complications arising from procedures include thrombosis caused by placement of peripherally inserted central catheters, pyoderma gangrenosum from sites of dermal trauma, and anetoderma of prematurity from cutaneous monitoring devices in neonates. Calcinosis cutis and decubitus ulcers are also hospital problems.
医源性皮肤损伤住院患者的范围从药物相关的并发症到与程序相关的并发症。常见的药物并发症包括药物反应伴嗜酸性粒细胞增多和全身症状（DRESS）、线性免疫球蛋白（Ig）A 大疱性皮病、史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症和急性全身性发疹性脓疱病。接触性皮炎可由洗必泰碘和聚维酮碘、医用粘合剂、外用术后软膏（最常见的是新霉素和杆菌肽）以及包括冠状动脉支架、起搏器和金属关节在内的内置假体引起。操作引起的并发症包括外周插入中心导管引起的血栓形成、皮肤创伤部位引起的坏疽性脓皮病和新生儿皮肤监测设备引起的早产儿萎缩性皮炎。钙沉着症和压疮也是医院的问题。
